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Reduction of cerebral oedema
Adult: 2.5 g (25 ml of a 10% solution) administered IV.
Intravenous
Torsades de pointes
Adult: With pulses: Loading dose of 1-2 g diluted in 50-100 ml of 5% dextrose inj over 5-60 minutes, followed by maintenance infusion at 0.5-1 g/hr as needed. Pulseless: 1-2 g diluted in 10 ml of 5% dextrose inj and given over 5-20 minutes.
Intravenous
Eclampsia
Adult: Typical loading dose: 4-5 g over 10-15 minutes, followed by either a continuous infusion of 1 g/hr (for at least 24 hr after the last seizure) or deep IM doses of 4-5 g into alternate buttocks every 4 hr (for at least 24 hr after the last seizure). If seizure recurs, an additional IV dose of 2-4 g may be given. Continue therapy until paroxysms cease. A serum magnesium level of 6 mg/100 mL is considered optimal for seizure control. Not to exceed 30-40 g per 24 hr.
Intravenous
Muscle stimulating effects of barium poisoning
Adult: 1-2 g administered IV.
Oral
Constipation
Adult: 5-10 g in 250 mL water.
Oral
Mild hypomagnesaemia
Adult: 3 g every 6 hr for 4 doses.
Parenteral
Hypomagnesaemia
Adult: IM admin: For mild deficiency: 1 g (8.12 mEq or 2 mL of the 50% solution) every 6 hr for 4 doses or based on serum magnesium levels. For severe deficiency: 2 mEq (0.5 mL of the 50% solution)/kg or up to 250 mg/kg within a 4-hr period if needed. IV admin: For symptomatic deficiency: 1-2 g over 5-60 minutes followed by maintenance infusion at 0.5-1 g/hr to correct the deficiency. For severe hypomagnesemia: 1-2 g/hr for 3-6 hr, then 0.5-1 g/hr as needed based on serum magnesium levels.
Topical/Cutaneous
Boils and carbuncles
Adult: Apply as a paste under dressing. Prolonged use is not recommended.
Child: Apply as a paste under dressing. Prolonged use is not recommended.
Child: Apply as a paste under dressing. Prolonged use is not recommended.