dexamethasone + neomycin + polymyxin b




Firma Chun Cheong
Concise Prescribing Info
Per mL susp/g oint Dexamethasone 0.1%, neomycin sulfate 3,500 IU, polymyxin B sulfate 6,000 IU
Ocular inflammation when concurrent use of an antimicrobial is judged necessary.
Dosage/Direction for Use
Ophth susp 1-2 drops in the conjunctival sac 4-6 times daily in mild cases, hrly in acute cases & being tapered to discontinuation as the inflammation subsides. Ophth oint Apply a small amount in the conjunctival sac tds or qds, or use as a supplement to the eye drops at bedtime.
Hypersensitivity. Viral diseases of the eye eg, dendritic keratitis, vaccinia, varicella, tubercular & fungal diseases of the eye. Do not use while wearing soft contact lenses. After uncomplicated removal of a foreign body from the cornea & in any other disorder or injury damaging the superficial corneal epithelium. Use in glaucoma only under physician's advice.
Special Precautions
Not for inj or ingestion. Prolonged use may result in glaucoma, w/ damage to the optic nerve, decrease of visual acuity & field of vision, & posterior subcapsular cataract formation. Monitor IOP regularly. Diseases causing thinning of the cornea or sclera. May mask or aggravate existing infection in acute purulent conditions of the eye. Increased hazard of secondary ocular infections in prolonged use. Cutaneous hypersensitivity. Avoid wearing contact lenses. Cross-sensitivity & cross-resistance between neomycin & other aminoglycosides. Systemic resorption of corticosteroids. May affect ability to drive or use machines. Pregnancy & lactation.
Adverse Reactions
Allergic sensitisation. Rash, itching, irritation, swelling, reddening, oedema of the conjunctiva & eyelid, conjunctival erythema or contact dermatitis. Elevated IOP w/ possible development of glaucoma; less frequently, optic nerve damage, posterior subcapsular cataract formation, delayed wound healing, perforation of the cornea. Secondary infection.
MIMS Class
Eye Antiseptics with Corticosteroids
ATC Classification
S01CA01 - dexamethasone and antiinfectives ; Belongs to the class of corticosteroids in combination with antiinfectives. Used in the treatment of eye diseases.
Maxitrol ophth oint
3.5 g x 1's
Maxitrol ophth susp
5 mL x 1's
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