Melbin

Melbin

metformin

Manufacturer:

Shiono Chemical

Distributor:

Main Life
Concise Prescribing Info
Contents
Metformin HCl
Dosage/Direction for Use
Initially, 500 mg in 2-3 divided doses. Max: 750 mg.
Administration
Should be taken with food.
Contraindications
Hypersensitivity. History of lactic acidosis. Renal/hepatic impairment. Severe CV or pulmonary disorders, severe intoxication, hypohydration. GI disorders eg, diarrhoea, vomiting. Severe ketosis, diabetic coma, prediabetic coma or IDDM. Severe infections, pre- & post-op or w/ serious external wounds. Malnutrition, inanition, marasmus, pituitary or adrenal dysfunction. Pregnancy. Elderly.
Special Precautions
Hypoglycemia, irregular or insufficient meal, strenuous physical exercise or w/ infections.
Adverse Reactions
Lactic acidosis. Serious & delayed hypoglycemia. Anorexia, nausea, vomiting, diarrhea, constipation, abdominal pain, abdominal distention; anemia, leukopenia, thrombopenia; eruption; hepatic impairment; ketosis; malaise, headache, heavy headedness, drowsiness, alopecia. Rhabdomyolysis.
Drug Interactions
Iodine contrast medium, nephrotoxic antibiotics, insulin, sulfonylamides, sulfonylureas, α-glucosidase inhibitors, insulin-sensitizing agent, troglitazone, anabolic steroids, guanethidine, salicylates, β-blockers, MAOIs, epinephrine, adrenocortical hormones, thyroid hormones, estrogen, diuretics, pyrazinamides, INH, nicotinic acid, phenothiazines.
MIMS Class
Antidiabetic Agents
ATC Classification
A10BA02 - metformin ; Belongs to the class of biguanides. Used in the treatment of diabetes.
Presentation/Packing
Form
Melbin tab 250 mg
Packing/Price
100's
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