Known hypersensitivity to mesna, other thiol compounds or to any of the excipients.
Notes: In the presence of autoimmune disease, there is an increased risk to develop allergic or anaphylactoid reactions (see also Adverse Reactions). Therefore, protection of the urinary tract with MESNA Stada should only be carried out in these patients after a careful risk-benefit assessment and under medical supervision.
As mesna is only indicated in combination with oxazaphosphorines, the contraindications which apply to cyclophosphamide, ifosfamide and trofosfamide should also be observed.
Please refer to Precautions and Use in Pregnancy & Lactation.