Methylprednisolone - oral

Patient Medicine Information
Why do I need this medicine?
Methylprednisolone is used relieve inflammation or suppress or reduce the strength of the body’s immune system. It is used to treat a wide variety of diseases such as asthma, lupus (autoimmune disease that causes inflammation), cancer of the blood cells, and inflammatory bowel disease (e.g. Crohn’s disease).

This medicine can also be used to prevent the body from rejecting a transplanted organ (e.g. bone marrow).

This medicine may be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take Methylprednisolone exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take this medicine together with food or immediately after a meal. Try to take it at the same time each day.

Methylprednisolone must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it suddenly as this may worsen your condition. Your doctor may want to reduce the dose of Methylprednisolone gradually before stopping it completely.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have any serious fungal infection as this medicine may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:

- heart disease
- liver disease
- kidney disease
- glaucoma (increased pressure in the eye) or cataracts (clouding of the lens of the eye)
- thyroid disease
- diabetes
- stomach problems
- epilepsy (fits or seizures)
- tuberculosis
- myasthenia gravis (muscle weakness disorder)
- osteoporosis (thinning of bones)

Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving this medicine to a child. If your child is taking Methylprednisolone, his height and growth development should be monitored regularly.

Inform your doctor if you have been recently vaccinated. Do not receive any vaccinations without first asking your doctor.

Avoid people who have chickenpox or measles. Inform your doctor right away if you do come into contact with people who have the said diseases.

For as long as you are taking this medicine, you may need to have regular tests for your blood pressure, glucose and electrolyte level to check your body’s response to the medicine. Your doctor will advise you about how often you need to have these tests.
What side effects could I experience?
Methylprednisolone may cause dizziness, tiredness or some problems with your eyesight. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

Other side effects include any of the following: headache, nausea, vomiting, increased appetite, indigestion, weight gain, excessive hair growth, and stomach pain.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

- unusual changes in mood or behaviour (being too depressed, agitated or having compulsive and impulsive behaviour)
- hallucination (seeing, hearing or feeling things that are not existent)
- breathlessness
- swelling of the face, legs, ankles or feet
- rashes
- muscle weakness

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- medicines to treat fungal infections e.g. itraconazole, ketoconazole, amphotericin B
- antibiotics e.g. clarithromycin, erythromycin, troleandomycin
- medicines for high blood pressure or heart disease e.g. diltiazem, mibefradil
- medicines used in organ transplant or certain immune disorders e.g. ciclosporin
- birth control pills e.g ethinylestradiol, norethindrone
- medicines to treat TB (lung infection known as tuberculosis) e.g. rifampicin
- medicines for epilepsy (fits or seizures) e.g. phenytoin , phenobarbital, carbamazepine
- medicines for stomach disorder e.g. cimetidine
- blood-thinning medicines e.g. aspirin, warfarin

This list does not include all medicines that may interact with Methylprednisolone.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid excessive consumption (more than 1 litre a day) of grapefruit juice.

Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on methylprednisolone - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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