Like all medicines, Metphar XR can cause side effects, although not everybody gets them. The following side effects may occur: Metphar XR may cause a very rare (may affect up to 1 user in 10,000) but very serious side effect called lactic acidosis (see Risk of lactic acidosis under Precautions). If this happens, patients must stop taking Metphar XR and contact a doctor or the nearest hospital immediately, as lactic acidosis may lead to coma.
Metphar XR may cause abnormal liver function tests and hepatitis (inflammation of the liver) which may result in jaundice (may affect up to 1 user in 10,000). If yellowing of the eyes and/or skin develops, contact the doctor immediately.
Other possible side effects are listed by frequency as follows: Very common (affects more than 1 person in 10): Diarrhoea, nausea, vomiting, stomach ache or loss of appetite. If these are experienced, do not stop taking the tablets as these symptoms will normally go away in about 2 weeks. It helps if the tablets are taken with or immediately after a meal.
Common (affects less than 1 person in 10, but more than 1 person in 100): Taste disturbance.
Very rare (affects less than 1 person in 10,000): Decreased vitamin B12 levels; Skin rashes including redness, itching and hives.
Reporting of side effects: If any side effects are experienced, talk to the doctor or pharmacist. This includes any possible side effects not listed in this monograph.