20-30 IU/kg once daily for 1-2 days. Moderate to severe haemorrhage
30-50 IU/kg once to bd for 1-5 days. Minor surgery
Loading dose: 40-60 IU/kg. Maintenance: 15-40 IU/kg once to bd or as continuous infusion for 7-10 days. Major surgery
Loading dose: 70-100 IU/kg Maintenance: 20-90 IU/kg once to bd or as continuous infusion for 10-12 days. Prophylaxis
25-40 IU/kg twice wkly.