Naproxen - oral

Patient Medicine Information
Why do I need this medicine?
Naproxen is used to help relieve pain and inflammation associated with ankylosing spondylitis (inflammation in joints of your spine), rheumatoid arthritis (inflammation in joints of fingers, wrist, feet, ankles), osteoarthritis (damage of joints' surfaces), and attacks of gout (abnormal metabolism of uric acid).

This medicine may also be used to treat pain associated with menstrual period.

Naproxen may be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take Naproxen exactly as directed by your doctor or according to the instructions on the label. Do not take more than or exceed the length of treatment instructed by your doctor.

Take it together with food or immediately after a meal.

Naproxen is available as conventional, modified-release, gastro-resistant and effervescent tablet, or as an oral suspension.

If you are taking the modified-release, sustained-release or extended-release type of tablet (usually labelled as "SR" or "ER"), swallow it whole. Do not divide, chew or crush the tablet.

If you are taking an oral suspension, shake the bottle well before you take it to ensure that the liquid is evenly mixed. Use the measuring spoon or cup provided to measure out your prescribed dose.

Naproxen also comes as an effervescent tablet. Dissolve the tablet in a glass (150 mL) of water, then drink the solution immediately. To ensure that there is no medicine left, rinse the empty glass with small amount of water and drink it.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the dose and course of your treatment depending on your condition.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.
When should I not use this medicine?
Do not take this medicine if you ever had a history of allergic reactions (rashes, breathlessness, swollen eyes) to Naproxen, other similar medicines for pain and inflammation such as non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin.

Alert your doctor if you have the following conditions:
  • active or a history of stomach ulcer or bleeding
  • history of stomach bleeding or perforation that is related to previous NSAID therapy
  • severe heart disease
  • severe liver disease
  • severe kidney disease
  • asthma, inflammation of mucous membranes in the nose, or hives related to aspirin use
as Naproxen may not be suitable for you.

This medicine should not be used to treat pain or after a coronary artery bypass graft surgery (procedure to improve and restore the blood flow in the heart).

Do not take Naproxen if you are on your 3rd trimester of pregnancy. If you become pregnant while being treated with this medicine, alert your doctor immediately. Naproxen may cause harm to your unborn child.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • asthma
  • risks of having heart problems e.g. high blood pressure, diabetes, high cholesterol levels, smoking
  • mild to moderate liver or kidney disease
  • Crohn’s disease (long-standing inflammatory disease of the intestines)
  • ulcerative colitis (inflammation of large intestines)
  • dehydration
  • low volume of circulating blood in the body
Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving this medicine to an elderly. Elderly may be more sensitive to the side effects.

If you are going for an operation, including minor surgery or dental work, inform your doctor or dentist that you are taking Naproxen.

Avoid long-term use of any painkillers.

For as long as you are taking Naproxen, you may need to have your regular tests (e.g. complete blood count, liver and kidney function test) to check your body’s response to the medicine. Your doctor will advise you about how often you need to have these tests.
What side effects could I experience?
Naproxen may cause dizziness, drowsiness or some problems with your eyesight. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: headache, nausea, vomiting, constipation, indigestion, stomach pain, heartburn (food or acid from your stomach backs up into your mouth, leaving a sour or bitter taste), diarrhoea, stomach wind, sweating, tiredness, muscle pain or weakness, ringing in the ears, difficulty sleeping, nervousness and swelling of ankles, feet or hand.

If you develop rashes, breathlessness, swollen mouth or face, stop taking Naproxen and inform your doctor quickly. These could be signs of an allergic reaction.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • pass out black, tarry stools or vomit coffee-ground-like vomitus
  • rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
  • chest pain, fast or irregular heartbeat
  • unusual bleeding or bruising
  • yellowing of the skin or eyes
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Do not take Naproxen if you are currently taking other NSAIDs (medicines used in pain and inflammation) such as diclofenac, ibuprofen, mefenamic acid, indometacin, ketoprofen, meloxicam, or piroxicam.

Inform your doctor and pharmacist if you are taking any of these medicines:
  • blood-thinning medicines e.g. aspirin, warfarin, heparin, clopidogrel
  • medicines for high blood pressure or heart disease e.g. captopril, losartan
  • diuretics or “water pills” e.g. furosemide, hydrochlorothiazide
  • lithium (medicine to treat depression)
  • probenecid (medicine for gout)
  • colestyramine (cholesterol-lowering medicine)
  • medicines used in organ transplant or certain immune disorders e.g. ciclosporin, tacrolimus
  • medicines used in cancer therapy e.g. methotrexate, pemetrexed
This list does not include all medicines that may interact with Naproxen.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Keep tablets in their original package to protect from light.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on naproxen - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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