Caution should be observed in patients with hyponatraemia or elevated serum osmolarity.
It is necessary to monitor fluid balance, serum electrolyte levels, acid-base balance, serum urea and blood ammonia levels during therapy. Laboratory monitoring should also include blood glucose, serum protein, creatinine and liver function tests.
There is at present no clinical experience of the use of Nephrotect in children.
Effects on ability to drive and use machines: Not relevant.