Neulastim

Neulastim

pegfilgrastim

Manufacturer:

Amgen

Distributor:

Zuellig
/
Agencia Lei Va Hong

Marketer:

Kerry Pharma
Concise Prescribing Info
Contents
Pegfilgrastim
Indications/Uses
Reduction in duration of neutropenia & incidence of febrile neutropenia in adults treated w/ cytotoxic chemotherapy for malignancy (w/ the exception of chronic myeloid leukaemia & myelodysplastic syndromes).
Dosage/Direction for Use
SC Adult One 6 mg single dose per chemotherapy cycle given into the thigh, abdomen or upper arm at least 24 hr following cytotoxic chemotherapy.
Contraindications
Hypersensitivity.
Special Precautions
Hypersensitivity occurring on initial or subsequent treatment. AML; myelodysplastic syndrome, chronic myelogenous leukaemia, secondary AML; sickle cell trait or disease. Do not use to increase dose of cytotoxic chemotherapy beyond established dosage regimens. Discontinue in case of preliminary signs of acute resp distress syndrome (ARDS); leukocyte count >50 x 109/L after expected nadir. Closely monitor patients who develop symptoms of capillary leak syndrome. Monitor urinalysis; spleen size; platelet count & haematocrit. Transient positive bone imaging findings. Latex-sensitive patients. Rare hereditary problems of fructose intolerance. Women of childbearing potential not using contraception. Pregnancy & lactation. Childn.
Adverse Reactions
Headache; nausea; bone pain. Thrombocytopenia, leukocytosis; musculoskeletal pain (myalgia, arthralgia, pain in extremity, back pain, musculoskeletal pain, neck pain); inj site pain, non-cardiac chest pain.
Drug Interactions
Potentiated myelosuppression w/ 5-fluorouracil (5-FU) or other antimetabolites.
MIMS Class
Haematopoietic Agents / Supportive Care Therapy
ATC Classification
L03AA13 - pegfilgrastim ; Belongs to the class of colony stimulating factors. Used as immunostimulants.
Presentation/Packing
Form
Neulastim inj (pre-filled syringe) 6 mg/0.6 mL
Packing/Price
1's
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Already a member? Sign in