NovoMix 30諾和銳30特充

NovoMix 30

insulin aspart + insulin aspart protamine

Manufacturer:

Novo Nordisk

Distributor:

Firma Chun Cheong
/
DKSH
Concise Prescribing Info
Contents
Per 100 U/mL Soluble insulin aspart 30%, protamine-crystallised insulin aspart 70%
Indications/Uses
Dosage/Direction for Use
SC Insulin naïve patients Type 2 DM Initially 6 u at breakfast & 6 u at dinner, or 12 u once daily at dinner. Once daily dose may be intensified to bd when reaching 30 u by splitting dose into equal breakfast & dinner doses (50:50). For bd-tds dosage, morning dose can be split into morning & lunchtime doses (tds dosing).
Administration
Should be taken with food: Administer immediately before or after meals.
Contraindications
Special Precautions
Do not administer IV/IM. Not to be used in insulin infusion pumps. Risk of hyperglycaemia & diabetic ketoacidosis w/ inadequate dosing or discontinuation of treatment in patients w/ type 1 diabetes. Risk of hypoglycaemia w/ excessive insulin dose, omitted meal or unplanned, strenuous physical exercise. Change in usual warning symptoms of hypoglycaemia in patients w/ greatly improved blood glucose control eg, intensified therapy, & w/ longstanding diabetes. Concomitant illness, especially infections & feverish conditions; diseases in the kidney, liver, or affecting the adrenal, pituitary or thyroid gland. Transfer to another type or brand of insulin; change in strength, brand (manufacturer), type, origin (human insulin, insulin analogue) &/or method of manufacture. Rotate inj site continuously to reduce risk of inj site reactions. Cases of CHF in combination w/ thiazolidinediones. May cause insulin Ab to form. May impair ability to drive & use machines. Pregnancy & lactation.
Adverse Reactions
Hypoglycaemia. Refraction anomalies, oedema, inj site reactions (pain, redness, hives, inflammation, bruising, swelling & itching at the inj site).
Drug Interactions
Reduced patient's insulin requirement w/ oral antidiabetics, MAOIs, non-selective β-blockers, ACE inhibitors, salicylates, anabolic steroids & sulfonamides. Increased patient's insulin requirement w/ OCs, thiazides, glucocorticoids, thyroid hormones, sympathomimetics, growth hormone & danazol. Masked symptoms & delayed recovery from hypoglycaemia w/ β-blockers. Either increased or decreased insulin requirements w/ octreotide/lanreotide. Intensified or reduced hypoglycemic effects w/ alcohol.
ATC Classification
A10AB05 - insulin aspart ; Belongs to the class of fast-acting insulins and analogues. Used in the treatment of diabetes.
Presentation/Packing
Form
NovoMix 30 FlexPen
Packing/Price
3 mL x 5 × 1's
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