Nutriflex Peri/Nutriflex Plus

Nutriflex Peri/Nutriflex Plus

Manufacturer:

B. Braun

Distributor:

DKSH
/
Four Star
Concise Prescribing Info
Contents
Per L Nutriflex Peri Upper chamber (400 mL): Isoleucine 2.34 g, leucine 3.13 g, lysine HCl 2.84 g (lysine 2.27 g), methionine 1.96 g, phenylalanine 3.51 g, threonine 1.82 g, tryptophan 0.57 g, valine 2.6 g, arginine monoglutamate 4.98 g (arginine 2.7 g, glutamic acid 2.28 g), histidine HCl monohydrate 1.69 g (histidine 1.25 g), alanine 4.85 g, aspartic acid 1.5 g, glutamic acid 1.22 g, glycine 1.65 g, proline 3.4 g, serine 3 g, Mg acetate tetrahydrate 0.86 g, Na acetate trihydrate 1.56 g, K dihydrogen phosphate 0.78 g, K hydroxide 0.52 g, Na hydroxide 0.5 g. Lower chamber (600 mL): Glucose monohydrate 88 g (glucose 80 g), NaCl 0.17 g, Ca chloride dihydrate 0.37 g. Electrolyte: Na 27 mmol, K 15 mmol, Mg 4 mmol, phosphate 5.7 mmol, acetate 19.5 mmol, Cl 31.6 mmol, Ca 2.5 mmol. Amino acid 40 g, nitrogen 5.7 g, carbohydrate 80 g. Total energy: 480 kCal. Per L Nutriflex Plus Upper chamber (400 mL): Isoleucine 2.82 g, leucine 3.76 g, lysine HCl 3.41 g (lysine 2.73 g), methionine 2.35 g, phenylalanine 4.21 g, threonine 2.18 g, tryptophan 0.68 g, valine 3.12 g, arginine monoglutamate 5.98 g (arginine 3.24 g, glutamic acid 2.74 g), histidine HCl monohydrate 2.03 g (histidine 1.5 g), alanine 5.82 g, aspartic acid 1.8 g, glutamic acid 1.47 g, glycine 1.98 g, proline 4.08 g, serine 3.6 g, Mg acetate tetrahydrate 1.23 g, Na acetate trihydrate 1.56 g, Na dihydrogen phosphate dihydrate 3.12 g, K hydroxide 1.4 g, Na hydroxide 0.23 g. Lower chamber (600 mL): Glucose monohydrate 165 g (glucose 150 g), Ca chloride dihydrate 0.53 g. Electrolyte: Na 37.2 mmol, K 25 mmol, Mg 5.7 mmol, phosphate 20 mmol, acetate 22.9 mmol, Cl 35.5 mmol, Ca 3.6 mmol. Amino acid 48 g, nitrogen 6.8 g, carbohydrate 150 g. Total energy: 792 kCal
Indications/Uses
Nutriflex Peri Parenteral nutrition for patients w/ mild to moderate catabolism when oral/enteral nutrition is impossible, insufficient or contraindicated. Nutriflex Plus Parenteral nutrition for patients w/ moderately severe catabolism when oral/enteral nutrition is impossible, insufficient or contraindicated.
Dosage/Direction for Use
Nutriflex Peri Individualised dosage via IV infusion into peripheral or central veins. Max: 40 mL/kg/day. Max infusion rate: 2.5 mL/kg/hr. Max duration: 10 days for applications via peripheral venous access. Childn 2-17 yr Max: 50 mL/kg/day. Nutriflex Plus Individualised dosage via IV infusion into central veins only. Max: 40 mL/kg/day. Max infusion rate: 1.6 mL/kg/hr. Childn 2-17 yr Max: 42 mL/kg/day.
Contraindications
Hypersensitivity. Inborn errors of amino acid metabolism; acidosis; hyperglycaemia not responding to insulin doses up to 6 u/hr; intracranial or intraspinal haemorrhage. Unstable circulatory status w/ vital threat (eg, states of collapse, shock, fluid overload, pulmonary oedema); acute MI & stroke; unstable metabolic condition (eg, coma of unknown origin, hypoxia, decompensated DM). Severe hepatic insufficiency & severe renal insufficiency in absence of renal replacement therapy. Should not be used in newborn infants, infants & toddlers <2 yr.
Special Precautions
Caution in case of increased serum osmolarity. Patients w/ impaired cardiac or renal function; insufficiencies of liver, adrenal glands, & lungs; damaged haematoencephalic barrier; DM; Na retention. Correct fluid, electrolyte or acid-base balance prior to infusion. Monitor blood glucose level. Reduce infusion rate or administer insulin if there is hyperglycaemia. Interrupt administration if blood glucose conc >14 mmol/L. Concurrent use of other IV glucose soln; soln containing Mg, Ca, & phosphate. Abrupt discontinuation may lead to hypoglycaemia, especially in childn <3 yr & patients w/ disturbed glucose metabolism; monitor for at least 30 min on the 1st day of abrupt discontinuation. Monitor serum electrolytes, water balance, acid-base balance, blood cell counts, coagulation status, & hepatic/renal function. Risk of fluid overload w/ pathological serum electrolyte conc, hyperhydration, pulmonary oedema & polyuria w/ too rapid infusion. Infusion in peripheral veins may cause thrombophlebitis. Risk of pseudoagglutination w/ simultaneous administration of blood in the same infusion set. Pregnancy. Not recommended during lactation.
Adverse Reactions
Rarely, nausea, vomiting, decreased appetite. Nutriflex Peri Vein irritation, phlebitis, thrombophlebitis.
Drug Interactions
Use w/ caution in patients receiving medicinal products that increase serum K conc (eg, K-sparing diuretics, ACE inhibitors, AIIA, cyclosporine, tacrolimus). Corticosteroids & adrenocorticotropic hormone are associated w/ Na & fluid retention.
MIMS Class
Parenteral Nutritional Products
ATC Classification
B05BA10 - combinations ; Belongs to the class of solutions for parenteral nutrition used in I.V. solutions.
Presentation/Packing
Form
Nutriflex Peri infusion
Packing/Price
1 L x 5 × 1's
Form
Nutriflex Plus infusion
Packing/Price
1 L x 5 × 1's
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Sign up for free
Already a member? Sign in