Nutriflex-Lipid Peri/Nutriflex Omega Special

Nutriflex-Lipid Peri/Nutriflex Omega Special

Manufacturer:

B. Braun

Distributor:

DKSH
/
Four Star
Concise Prescribing Info
Contents
Per 1,250 mL Nutriflex-Lipid Peri Glucose monohydrate 88 g (anhydrous glucose 80 g), Na dihydrogen phosphate dihydrate 1.17 g, Zn acetate dihydrate 6.625 mg, soya bean oil 25 g, medium-chain triglycerides 25 g, isoleucine 2.34 g, leucine 3.13 g, lysine HCl 2.84 g (lysine 2.26 g), methionine 1.96 g, phenylalanine 3.51 g, threonine 1.82 g, tryptophan 0.57 g, valine 2.6 g, arginine 2.7 g, histidine HCl monohydrate 1.69 g (histidine 1.25 g), alanine 4.85 g, aspartic acid 1.5 g, glutamic acid 3.5 g, glycine 1.65 g, proline 3.4 g, serine 3 g, Na hydroxide 0.8 g, NaCl 1.081 g, Na acetate trihydrate 0.544 g, K acetate 2.943 g, Mg acetate tetrahydrate 0.644 g, Ca chloride dihydrate 0.441 g. Amino acid 40 g, total nitrogen 5.7 g, carbohydrate 80 g, lipid 50 g. Electrolyte: Na 50 mmol, K 30 mmol, Mg 3 mmol, Ca 3 mmol, Zn 0.03 mmol, Cl 48 mmol, acetate 40 mmol, phosphate 7.5 mmol. Energy: 955 kCal. Per 1,250 mL Nutriflex Omega Special Glucose monohydrate 198 g (anhydrous glucose 180 g), Na dihydrogen phosphate dihydrate 3.12 g, Zn acetate dihydrate 8.78 mg, medium-chain triglycerides 25 g, refined soya bean oil 20 g, omega-3-acid triglycerides 5 g, isoleucine 4.11 g, leucine 5.48 g, lysine HCl 4.98 g (lysine 3.98 g), methionine 3.42 g, phenylalanine 6.15 g, threonine 3.18 g, tryptophan 1 g, valine 4.51 g, arginine 4.73 g, histidine HCl monohydrate 2.96 g (histidine 2.19 g), alanine 8.49 g, aspartic acid 2.63 g, glutamic acid 6.14 g, glycine 2.89 g, proline 5.95 g, serine 5.25 g, Na hydroxide 1.464 g, NaCl 0.473 g, Na acetate trihydrate 0.313 g, K acetate 4.611 g, Mg acetate trihydrate 1.137 g, Ca chloride dihydrate 0.779 g. Amino acid 71.8 g, total nitrogen 10 g, carbohydrate 180 g, lipid 50 g. Electrolyte: Na 67 mmol, K 47 mmol, Mg 5.3 mmol, Ca 5.3 mmol, Zn 0.04 mmol, Cl 60 mmol, acetate 60 mmol, phosphate 20 mmol. Energy: 1,475 kCal
Indications/Uses
Nutriflex-Lipid Peri Parenteral nutrition for patients w/ mild to moderately severe catabolism when oral/enteral nutrition is impossible, insufficient or contraindicated. Nutriflex Omega Special Parenteral nutrition for patients w/ moderate to severe catabolism when oral/enteral nutrition is impossible, insufficient or contraindicated.
Dosage/Direction for Use
Nutriflex-Lipid Peri Individualised dosage via IV infusion (especially suitable for infusion into peripheral veins). Max rate of infusion: 2.5 mL/kg/hr. Max duration: 7 days. Adult Max: 40 mL/kg/day. Childn 6-14 yr Max: 30 mL/kg/day, 3-5 yr Max: 45 mL/kg/day. Nutriflex Omega Special Adult Individualised dosage via central venous infusion only. Max: 35 mL/kg/day. Max rate of infusion: 1.7 mL/kg/hr. Max amount of energy: 40 kCal/kg/day.
Contraindications
Disturbances of amino acid & lipid metabolism, hyperkalaemia, unstable metabolism, hyperglycaemia not responding to insulin doses up to 6 u/hr, acidosis, intrahepatic cholestasis, severe hepatic insufficiency, manifest cardiac insufficiency, aggravating haemorrhagic diatheses, acute phases of cardiac infarction & stroke, acute thromboembolism & lipid embolism, unstable circulatory status w/ vital threat, inadequate cellular oxygen supply, states of hyperhydration, electrolyte & fluid disturbances, acute pulmonary oedema, decompensated cardiac insufficiency. Hypersensitivity to egg or soy protein. Should not be used in neonates, infants & childn <2 yr. Nutriflex-Lipid Peri Hyponatraemia, severe renal insufficiency. Nutriflex Omega Special Hypersensitivity to fish or peanut oil. Hypernatraemia, severe renal insufficiency w/o access to haemofiltration or dialysis.
Special Precautions
Exercise caution in cases of increased serum osmolarity; patients w/ impaired cardiac or renal function. Correct fluid, electrolyte or acid-base imbalance before the start of infusion. Monitor serum triglyceride & blood glucose conc. Reduce dose or interrupt administration if blood glucose conc >14 mmol/L. Immediately interrupt infusion in case of any sign or symptom of anaphylactic reaction. Increased urinary excretion of trace elements, especially copper & Zn, w/ IV infusion of amino acids. Risk of pseudoagglutination w/ simultaneous administration of blood in the same infusion set. Controls of serum ionogramme, water balance, acid-base balance & during long-term administration, blood cell counts, coagulation status & hepatic function are necessary. Fat content may interfere w/ certain laboratory measurements (eg, bilirubin, lactate dehydrogenase, oxygen saturation). Substitution of electrolytes, vit & trace elements may be necessary as required. Pregnancy & lactation. Nutriflex Omega Special Risk of fluid overload w/ pathological serum electrolyte conc, hyperhydration & pulmonary oedema w/ too rapid infusion. Patients w/ DM or renal failure; blood coagulation disorders or suspected vit K deficiency. Childn & adolescents.
Adverse Reactions
Nutriflex-Lipid Peri Slight increase in temp, flush, cold sensation, shivering, loss of appetite, nausea, vomiting, resp distress, headache, pain in the back, bones, chest & lumbar region, hypotension, HTN, hypersensitivity reactions, hot flushes or bluish discoloration of the skin. Nutriflex Omega Special Nausea, vomiting, loss of appetite. Rarely, allergic reactions, drowsiness, HTN or hypotension, flush, dyspnoea, cyanosis, erythema, headache, elevated body temp, sweating, feeling cold, chills, pain in the back, bones, chest & lumbar region.
Drug Interactions
Increased plasma lipolysis followed by a transient decrease in triglyceride clearance w/ heparin. Soya-bean oil (has natural content of vit K1) may interfere w/ therapeutic effect of coumarin derivatives. Use w/ caution in patients receiving drugs that increase serum K conc (eg, K-sparing diuretics, ACE inhibitors, cyclosporine, tacrolimus).
MIMS Class
Parenteral Nutritional Products
ATC Classification
V06DX - Other combinations of nutrients ; Used as general nutrients.
B05BA01 - amino acids ; Belongs to the class of solutions for parenteral nutrition used in I.V. solutions.
Presentation/Packing
Form
Nutriflex-Lipid Peri infusion
Packing/Price
1250 mL x 5 × 1's;1875 mL x 5 × 1's
/hongkong/image/info/nutriflex-lipid peri infusion/1,875 ml?id=bfbd59b9-e120-4790-86ed-a80a010c8cf5
/hongkong/image/info/nutriflex-lipid peri infusion/1,250 ml?id=ddf837ce-357a-4692-b248-a38d00fe01ae
Form
Nutriflex Omega Special infusion
Packing/Price
1250 mL x 5 × 1's;1875 mL x 5 × 1's
/hongkong/image/info/nutriflex omega special infusion/1,250 ml?id=a7a4b77f-b62c-40d6-9aa7-a80a010c8cd8
/hongkong/image/info/nutriflex omega special infusion/1,875 ml?id=e4bf471b-150b-4b06-ae84-a380010ba096
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