Ondansetron Fresenius

Ondansetron Fresenius Caution For Usage

ondansetron

Manufacturer:

Fresenius Kabi

Distributor:

Zuellig
/
The Glory Medicina
Full Prescribing Info
Caution For Usage
Special Precautions for Disposal and Other Handling: The solution must not be sterilised in an autoclave.
Ondansetron Injection should only be admixed with those infusion solutions which are recommended: Dextrose 5%; Ringer Lactate; Sodium Chloride 0.9%; Mannitol 10%.
The stability of Ondansetron Injection after dilution with the recommended infusion fluids have been demonstrated in concentrations 0.16 mg/ml and 0.64 mg/ml.
Compatibility with other drugs: The following drugs may be administered via the Y-site of Ondansetron Injection.
Cisplatin: Concentrations up to 0.48 mg/ml (e.g. 240 mg in 500 ml) administered over one to eight hours.
Carboplatin: Concentrations in the range 0.18 mg/ml to 9.9 mg/ml (e.g. 90 mg in 500 ml to 990 mg in 100 ml), administered over ten minutes to one hour.
Etoposide: Concentrations in the range 0.14 mg/ml to 0.25 mg/ml (e.g. 72 mg in 500 ml to 250 mg in 1 litre), administered over thirty minutes to one hour.
Ceftazidime: Doses in the range 250 mg to 2000 mg reconstituted with Water for Injections BP as recommended by the manufacturer (e.g. 2.5 ml for 250 mg and 10 ml for 2g ceftazidime) and given as an intravenous bolus injection over approximately five minutes.
Cyclophosphamide: Doses in the range 100 mg to 1g, reconstituted with Water for Injections BP, 5 ml per 100 mg cyclophosphamide, as recommended by the manufacturer and given as an intravenous bolus injection over approximately five minutes.
Doxorubicin: Doses in the range 10-100mg reconstituted with Water for Injections BP, 5 ml per 10 mg doxorubicin, as recommended by the manufacturer and given as an intravenous bolus injection over approximately 5 minutes.
The solution is to be visually inspected prior to use (also after dilution). Only clear solutions practically free from particles should be used.
The diluted solutions should be stored protected from light.
Any unused product or waste material should be disposed of in accordance with local requirements.
Incompatibilities: This medicinal product must not be mixed with other medicinal products except those previously mentioned in Special Precautions for Disposal and Other Handling.
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