GSK Consumer


Agencia Lei Va Hong
Full Prescribing Info
Xylometazoline hydrochloride.
Metered-dose nasal spray, gel, nebuliser and nasal drops for adults contain 0.1% of xylometazoline hydrochloride; nasal drops and metered-dose nasal spray for children contain 0.05% of xylometazoline hydrochloride, and Benzalkonium chloride as preservative.
The gel and / 0.1% metered-dose nasal spray (Menthol) also include flavoring substances. 1 spray puff from the metered-dose nasal spray corresponds to 0.14 mg (0.1%) and 0.035 mg (0.05%) respectively of xylometazoline hydrochloride.
Otrivin is used for various types of colds. It is designed to be applied in the nostrils, where it exerts a vasoconstricting effect thereby decongesting the mucosa of the nose and the throat.
This effect allows patients with colds to breathe more easily through the nose. The action of Otrivin is felt within a few minutes and lasts for several hours. Otrivin contains ingredients which help prevent the nasal mucosa drying out. Due to its prolonged action, the gel formulation is particularly indicated for facilitating nasal breathing during the night.
Dosage/Direction for Use
Unless otherwise prescribed by the doctor, the patient must keep to the following dosage recommendations: Infants and children under 2 years old, only under medical prescription, and children 2-6 years old: 0.05% nasal drops and metered-dose nasal spray: 1-2 drops of solution or 1 spray puff with the 0.05% metered-dose nasal spray 1-2 times a day in each nostril are usually sufficient. Do not exceed 3 applications per day.
Adults and children over 6 years: 0.1% nasal drops, nebuliser and metered-dose nasal spray: 2-3 drops of solution or 1 spray puff from 0.1% nebuliser or metered-dose nasal spray in each nostril 3-4 times daily. Gel: Apply a small amount of gel as deeply as possible into each nostril 3-4 times per day. The last application will usually take place shortly before bedtime. In children under 6 years, only the 0.05% nasal drop solution or metered-dose nasal spray should be used.
If the patient have had surgery involving the head, it is up to the doctor to decide whether the patient can use Otrivin. The limitation also applies to all other vasoconstrictive products used in the nose. Otrivin must not be used in the case of dry nasal mucosa (rhinitis sicca) or in the case of acute (closed-angle) glaucoma. Patients who are allergic to any of the ingredients in Otrivin must not use this medicinal product.
Special Precautions
As with other medicinal products for colds, Otrivin can lead to sleep and vision problems or episodes of dizziness which are evidence of oversensitivity to the product.
Consult a doctor if these effects are very disruptive, cold persists or gets worse, or other problems appear.
Otrivin must be used with care in the case of hypertension, cardio-vascular disease, thyroid hyperactivity or diabetes (Diabetes mellitus).
Otrivin must not be used for more than a week without medical advice because over a longer period of use, rebound congestion of the nasal mucosa (rhinitis medicamentosa) may appear. This would be very similar to the symptoms of cold.
Do not use the 0.1% drops, nebuliser, metered-dose nasal spray or gel in children under 6 years old.
The Otrivin 0.05% nasal drops and metered-dose nasal spray must not be used without a medical prescription in children under 2 years old and must be administered under adult supervision in children under 6 years old.
Inform the doctor, pharmacist or chemist if the patient suffers from another medical condition, allergic, already taking or using other medicinal products either internally or externally (even when as self-medication).
Use In Pregnancy & Lactation
If the patient is pregnant or breast feeding, please consult the doctor before using Otrivin.
Side Effects
Using Otrivin can cause the following side-effects: occasionally, a burning sensation in the nose and throat, local irritation, nausea, headaches and dryness of the nasal mucosa. In very rare cases insomnia or allergic reactions with respiratory problems may also appear.
If the patient notices side-effects that are not mentioned, please tell the doctor or pharmacist.
Medicinal products should be kept out of the reach of children.
For more in-depth information, consult the doctor or pharmacist (especially with regard to the 0.05% nasal drops and metered-dose nasal spray for children under 6 years old), who have access to detailed information for healthcare professionals.
Patient Counseling Information
Method for using the metered-dose nasal spray and the nebuliser: Metered-dose nasal spray (without gas propellant): Remove protective cap. Before using for the first time, pump several times until an even mist appears. Place the nozzle of the device in the nostril and exert pressure firmly, once only, on the collar of the metered-dose nasal spray. For subsequent applications, the metered dose nasal spray is instantly ready for use without prior pumping.
Nebuliser: Place the nozzle of the device in the nostril and exert pressure firmly, once only, on the sides of the nebuliser, remove the nozzle before releasing the presure. Inhaling slightly through the nose when pressure is applied ensures optimal dispersion of the nebuliser mist. Replace the protective cap after use.
Please keep to the doses which appear in the package leaflet or prescribed by your doctor. If you feel that the medicinal product is not effective enough or on the contrary, it is too effective, please consult your doctor or pharmacist.
ATC Classification
R01AA07 - xylometazoline ; Belongs to the class of topical sympathomimetic agents used as nasal decongestants.
Nasal drops 0.05% x 10 mL. 0.1% x 10 mL. Nasal spray 0.05% x 10 mL. 0.1% x 10 mL.
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Sign up for free
Already a member? Sign in