Paracetamol B. Braun Solution for Infusion

Paracetamol B. Braun Solution for Infusion Special Precautions

paracetamol

Manufacturer:

B. Braun

Distributor:

DKSH
/
Four Star
Full Prescribing Info
Special Precautions
Prolonged or frequent use is discouraged. It is recommended that a suitable analgesic oral treatment will be used as soon as this route of administration is possible.
In order to avoid the risk of overdose, check that other medicines administered do not contain either paracetamol or propacetamol. The dose may require adjustment (see Dosage & Administration).
Doses higher than those recommended entail the risk of very serious liver damage. Clinical signs and symptoms of liver damage (including fulminant hepatitis, hepatic failure, cholestatic hepatitis, cytolytic hepatitis) are usually first seen after two days of drug administration with a peak seen, usually after 4 - 6 days. Treatment with antidote should be given as soon as possible (see Overdosage).
Paracetamol should be used with caution in cases of: hepatocellular insufficiency; severe renal insufficiency (creatinine clearance ≤ 30 ml/min) (see Dosage & Administration and Pharmacology: Pharmacokinetics under Actions); chronic alcoholism; chronic malnutrition (low reserves of hepatic glutathione); dehydration; patients suffering from a genetically caused G-6-PD deficiency (favism), the occurrence of a haemolytic anaemia is possible due to the reduced allocation of glutathione following the administration of paracetamol.
This medicinal product contains less than 1 mmol sodium (23 mg) per container, i.e. essentially 'sodium-free'.
Effects on ability to drive and use machines: Not relevant.
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