Adult: Initially, 50 mcg once daily, in conjunction w/ activated vit D and Ca supplement. Active forms of vit D and Ca supplement may require adjustment based on albumin-corrected serum Ca concentration. Dose may be increased in increments of 25 mcg every 4 wk up to max of 100 mcg if serum Ca cannot be maintained >8 mg/dL w/o an active form of vit D and/or oral Ca supplementation. May be decreased to Min of 25 mcg once daily if total serum Ca is repeatedly >9 mg/dL after the active form of vit D has been discontinued and Ca supplement has been decreased to a dose sufficient to meet daily needs. Maintenance: Use the lowest dose that achieves albumin-corrected serum Ca w/in the lower half of the normal range (i.e. 8-9 mg/dL).