In worldwide controlled clinical studies, the following adverse events have been reported in adults and paediatric patients.
Autonomic Nervous System:
Altered lacrimation, altered salivation, flushing, hypoesthesia, impotence, increased sweating, thirst.
Body as a Whole:
Angioneurotic oedema, asthenia, back pain, blurred vision, chest pain, earache, eye pain, fever, leg cramps, malaise, rigors, tinnitus, viral infection, weight gain.
Hypertension, hypotension, palpitations, supraventricular tachyarrhythmias, syncope, tachycardia.
Central and Peripheral Nervous System:
Blepharospasm, dizziness, dysphonia, hypertonia, migraine, paresthesia, tremor, vertigo.
Altered taste, anorexia, constipation, diarrhoea, dyspepsia, flatulence, gastritis, hiccup, increased appetite, nausea, stomatitis, toothache, vomiting.
Agitation, amnesia, anxiety, confusion, decreased libido, depression, impaired concentration, insomnia, irritability, paroniria.
Breast pain, dysmenorrhoea, menorrhagia, vaginitis.
Bronchitis, bronchospasm, coughing, dyspnea, epistaxis, haemoptysis, laryngitis, nasal dryness, pharyngitis, sinusitis, sneezing.
Skin and Appendages:
Dermatitis, dry hair, dry skin, photosensitivity reaction, pruritus, purpura, rash, urticaria.
Altered micturition, urinary discoloration, urinary incontinence, urinary retention.