Full Prescribing Info
Excipients/Inactive Ingredients: Croscarmellose Sodium; Lactose monohydrate; Magnesium Stearate, Povidone, Sodium Lauryl Sulfate.
Pharmacology: pms-EZETIMIBE works by decreasing the absorption of cholesterol in the small intestine.
Cholesterol is one of several fatty substances found in the bloodstream. The total cholesterol is made up mainly of low density lipoprotein cholesterol and high density lipoprotein cholesterol (LDL and HDL cholesterol).
LDL cholesterol is often called "bad" cholesterol because it can build up in the walls of the arteries forming plaque. Eventually this plaque build-up can lead to a narrowing of the arteries. This narrowing can slow or block blood flow to vital organs such as the heart and brain. This blocking of blood flow can result in a heart attack or stroke.
HDL cholesterol is often called "good" cholesterol because it helps keep the bad cholesterol from building up in the arteries and protects against heart disease.
Triglycerides are another form of fat in the blood that may increase the risk for heart disease.
pms-EZETIMIBE may be taken alone or with other cholesterol-lowering medicines known as statins, in addition to diet and other lifestyle changes (see Interactions). pms-EZETIMIBE adds to the cholesterol-lowering effect of statins. Statins lower cholesterol in a different way; they work in the liver.
pms-EZETIMIBE helps to reduce total cholesterol, LDL, and apolipoprotein B in the management of hyperlipidaemias.
Dosage/Direction for Use
Usual dose: pms-EZETIMIBE should be taken as directed.
Continue taking other cholesterol-lowering medicines known as statins unless the doctor tells to stop.
If the patient is taking a statin, pms-EZETIMIBE can be taken at the same time.
Even if the patient is taking medication to treat high cholesterol, it is important to have cholesterol measured regularly. Know the cholesterol levels and goals.
Missed dose: In case of a missed dose, just resume the usual schedule of one tablet daily. Or contact the doctor or pharmacist.
Take pms-EZETIMIBE only as prescribed. If pms-EZETIMIBE has been taken more than necessary, contact the doctor or pharmacist.
In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Center immediately, even if there are no symptoms.
Patients who are hypersensitive (allergic) to ezetimibe or any of the nonmedicinal ingredients should not take pms-EZETIMIBE.
Patients with liver disease, active or unexplained increases in liver enzymes (blood tests of liver function) should not take pms-EZETIMIBE together with a statin.
Patients who are pregnant should not take together with a statin.
Patients who are nursing should not take pms-EZETIMIBE together with a statin.
Special Precautions
Serious Warnings and Precautions: Liver disease (Hepatitis); Pancreas disease (Pancreatitis); Muscle pain (Myopathy/Rhabdomyolysis, myalgia); Severe allergic reaction (Anaphylaxis).
Before using pms-EZETIMIBE, talk to the doctor if the patient: Is pregnant, plans to become pregnant or thinks she might be pregnant.
Is breast-feeding; pms-EZETIMIBE may be passed in the milk to the baby.
Has now or has had in the past any medical problems (including liver disease or liver problems).
Side Effects
Ezitimibe is generally well tolerated.
When used alone, the following common side effects have been reported: abdominal pain; diarrhea; flatulence; tiredness; viral infection; throat infection (pharyngitis); nose infection (sinusitis); joint pain (arthralgia); back pain; and coughing.
The following uncommon side effects have been reported: elevations in some laboratory blood tests of liver (transaminases) or muscle (CK) function; indigestion; heartburn; nausea; muscle spasms; neck pain; decreased appetite; hot flush; high blood pressure; chest pain and pain.
When used with a statin, the following common side effects have been reported: headache; tiredness; abdominal pain; diarrhea; joint pain (arthralgia); muscle pain (myalgia); back pain; throat infection (pharyngitis); nose infection (sinusitis); upper chest infection (respiratory tract); and changes in certain laboratory blood tests.
The following uncommon side effects have been reported: tingling sensation; dry mouth; gastritis; itching; rash; hives; muscular weakness; pain in arms and legs; unusual tiredness or weakness; and swelling, especially in the hands and feet.
In general use, the following side effects have been reported: raised red rash, sometimes with target-shaped lesions; dizziness; depression; tingling sensation; constipation; and unusual tiredness or weakness.
Contact the doctor in case of persistent and severe muscle aches or pains with no obvious explanation at any time after starting to take pms-EZETIMIBE.
If pms-EZETIMIBE has been prescribed with a statin, the doctor will order routine blood tests to check the liver function before and after starting treatment.
Talk to the doctor in case of medical problem that may be related to pms- EZETIMIBE. (See table.)

Click on icon to see table/diagram/image

This is not a complete list of side effects. For any unexpected effects while taking pms-EZETIMIBE, contact the doctor or pharmacist.
Drug Interactions
Always tell the doctor about all drugs, including herbal preparation, the patient is taking or plans to take, as well as those obtained without a prescription.
Drugs that may interact with pms-EZETIMIBE include: Cyclosporine; Cholestyramine (a resine/bile acid sequestrant) or any other bile acid sequestrant. In that case, pms-EZETIMIBE should be taken at least 2 hours before or 4 hours after taking the bile acid sequestrant; Fibrates.
Keep your medicine between 25°C. Protect from moisture and light.
MIMS Class
Dyslipidaemic Agents
ATC Classification
C10AX09 - ezetimibe ; Belongs to the class of other lipid modifying agents.
Tab 10 mg x 3 x 10's.
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Sign up for free
Already a member? Sign in