pms-Topiramate Description





Full Prescribing Info
Each tablet contains 25 mg, 50 mg or 100 mg topiramate.
Proper Name: Topiramate.
Chemical Name: 2, 3:4, 5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate.
Molecular formula: C12H21NO8S.
Molecular mass: 339.36 g/mol.
Physicochemical Properties: Description: Topiramate is a white crystalline powder having a bitter taste. Topiramate is most soluble in alkaline solutions containing sodium hydroxide or sodium phosphate with a pH of 9 to 10.
Solubility: It is freely soluble in acetone, chloroform, dimethyl sulfoxide and ethanol. The solubility in water is 9.8 mg/mL.
pH: Its saturated solution has a pH of 6.3.
Excipients/Inactive Ingredients: Colloidal Silicon Dioxide, Copovidone, Lactose Monohydrate, Magnesium Stearate, Sodium Starch Glycolate.
Tablet coatings: Polyethylene Glycol, Titanium Dioxide.
25 mg: Hydroxypropyl Methylcellulose, Polydextrose, Triethyl Citrate.
50 mg & 100 mg: Iron Oxide Yellow, Polyvinyl Alcohol, Talc.
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