Overview: Bile acid sequestering agents may interfere with the action of ursodiol by reducing absorption. Aluminum-based antacids adsorb bile acids in vitro and may act in the same manner as sequestering agents, thereby interfering with the action of ursodiol. Ursodiol has been shown to be an inducer of CYP3A however the clinical relevance is not known. Metabolic interactions with compounds metabolized by cytochrome P4503A are to be expected.
Drug-Drug Interactions: See Table 7.
Click on icon to see table/diagram/image
Drug-Food Interactions: Interactions with food have not been established.
Drug-Herb Interactions: Interactions with herbal products have not been established.
Drug-Laboratory Interactions: Interactions with laboratory tests have not been established.