Prochlorperazine Actavis

Prochlorperazine Actavis





Agencia Lei Va Hong
Concise Prescribing Info
Prochlorperazine maleate
Listed in Dosage.
Dosage/Direction for Use
Adult Vertigo & Meniere's syndrome 5 mg tds. Max: 30 mg/day. Prevention of nausea & vomiting 5-10 mg tds. Treatment of nausea & vomiting 20 mg followed, if necessary, by 10 mg 2 hr later. Adjunct in short-term management of anxiety 15-20 mg daily in divided doses. Max: 40 mg daily in divided doses. Schizophrenia & other psychotic disorders 75-100 mg daily. Dosage regimen: Initially 12.5 mg bd for 7 days, increased by 12.5-mg increments at 4-7 days interval.
May be taken with or without food.
Childn <12 yr. Lactation.
Special Precautions
Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Monitor complete blood count. Patients w/ liver or renal dysfunction, jaundice, Parkinson's disease, hypothyroidism, cardiac failure, CV disease, family history of QT prolongation, phaeochromocytoma, myasthenia gravis, prostate hypertrophy, narrow-angle glaucoma, agranulocytosis, epilepsy or history of seizures. Withdraw gradually. Avoid contact w/ skin & exposure to direct sunlight. May impair ability to drive or operate machinery. Elderly. Pregnancy.
Adverse Reactions
Mild leucopenia, hyperprolactinemia, tremors, acute dyskinesia, dystonia, akathisia, ocular changes, cardiac arrhythmias, postural hypotension, skin rash.
Drug Interactions
Epinephrine, alcohol, barbiturates, opioid analgesics, anxiolytics, hypnotics, sibutramine, antiarrhythmics, sotalol, TCA, terfenadine, other antipsychotics, antacids, kaolin, lithium, antiparkinson drugs, sulphonylureas, amphetamine, pramipexole, ropinirole, apomorphine, levodopa, lisuride, bromocriptine, cabergoline, pergolide, clonidine, guanethidine, anticholinergics, α-blockers, Ca-channel blockers, desferrioxamine.
ATC Classification
N05AB04 - prochlorperazine ; Belongs to the class of phenothiazine antipsychotics with piperazine structure.
Prochlorperazine Actavis tab 5 mg
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