Progesterone - Oral

Patient Medicine Information
Why do I need this medicine?
Progesterone is a natural female hormone used to prevent abnormal thickening of the lining of the womb after years of menopause in women receiving hormone replacement therapy (HRT).

This medicine may also be used in the management of absence of menstruation.
How do I take this medicine?
Take Progesterone exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take this medicine on an empty stomach.

It is best to take Progesterone just before you go to bed. Try to take it at the same time each day.

If you have difficulties swallowing the capsule, take it with a glass of water on an upright or standing position.

Progesterone must be taken regularly for it to be effective. Continue taking it even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • blood clot disorder
  • recent heart attack
  • recent stroke
  • liver disease
  • known, suspected or a history of breast cancer
  • unexplained or unusual vaginal bleeding
  • porphyria (an inherited disorder that may cause skin or nerve problems)
as this medicine may not be suitable for you.

Do not take Progesterone if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. Progesterone may cause harm to your unborn child. You must use proven birth control methods while taking this medicine.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • epilepsy (fits or seizures)
  • asthma
  • migraine
  • heart disease or risk factors for heart disease e.g. high blood pressure, high cholesterol, diabetes
  • kidney disease
  • history of depression
Let your doctor know if you are breastfeeding.

If you are going for any laboratory tests, inform your doctor that you are being treated with Progesterone as it can interfere with certain tests.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Your doctor may need to do routine physical examination while you are being treated with this medicine.
What side effects could I experience?
Progesterone may cause dizziness, drowsiness or some problems with your eyesight. If affected, do not drive or take part in any activity in which you need to be alert.

Progesterone may cause any of the following side effects: headache, tiredness, stomach pain, constipation, bloating, diarrhoea, nausea, vomiting, joint or muscle pain, breast pain or tenderness and vaginal discharge.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • difficulty breathing or chest discomfort
  • severe headache or migraine
  • visual disturbances
  • yellowing of the whites of your eyes or skin
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for Parkinson’s disease (disorder that affects movement of a person, causing symptoms such as tremors, muscle stiffness, slowed movement and impaired balance or walking) e.g. bromocriptine
  • medicines for organ transplant or immune disorder e.g. ciclosporin
  • medicines for TB e.g. rifampicin
  • medicines for fungal infections e.g. ketoconazole
  • medicines for epilepsy e.g. carbamazepine, phenobarbital, phenytoin
This list does not include all medicines that may interact with Progesterone.

Always notify your doctor or pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on Progesterone - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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