Protaphane/Protaphane Penfill is an intermediate-acting insulin suspension that contains biosynthetic [recombinant deoxyribonucleic acid (DNA) origin, produced in Saccharomyces cerevisiae] human insulin.
One IU (International Unit) corresponds to 0.035 mg of anhydrous human insulin.
Protaphane: 1 ml contains 100 IU of insulin human.
1 vial contains 10 ml equivalent to 1,000 IU.
Protaphane is a suspension of isophane (NPH) insulin.
Protaphane Penfill: Protaphane HM Penfill cartridges are designed for use with Novo Nordisk insulin delivery systems and NovoFine needles. The cartridges should only be used in combination with products that are compatible therewith and allow the cartridge to function safely and effectively.
Excipients/Inactive Ingredients: Zinc chloride, glycerol, metacresol, phenol, disodium phosphate dihydrate, sodium hydroxide/hydrochloric acid (for pH adjustment), protamine sulphate and water for injections.