Remeron SolTab

Remeron SolTab

mirtazapine

Manufacturer:

MSD

Distributor:

Zuellig
/
Agencia Lei Va Hong

Marketer:

A. Menarini
Concise Prescribing Info
Contents
Mirtazapine
Indications/Uses
Dosage/Direction for Use
Adult including elderly Usual daily dose 15-45 mg. Starting dose: 15 or 30 mg.
Administration
May be taken with or without food: Place tab on tongue & allow to disintegrate then, swallow w/o water.
Contraindications
Hypersensitivity. Concomitant use w/ MAOIs.
Special Precautions
Risk of suicide/suicidal thoughts or clinical worsening; bone marrow depression; jaundice; akathisia/psychomotor restlessness; hyponatremia; serotonin syndrome. Patients w/ epilepsy & organic brain syndrome; hepatic or renal impairment; cardiac disease eg, conduction disturbance, angina pectoris & recent MI; low BP; DM; schizophrenia or other psychotic disturbances; history of mania/hypomania; micturition disturbances, acute narrow-angle glaucoma & increased IOP; known CVD or family history of QT prolongation & patients concomitantly using other medicines that may prolong the QTc interval. Abrupt termination of treatment may result in w/drawal symptoms. Rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency. Phenylketonurics. Minor to moderate influence on the ability to drive & use machines. Pregnancy & lactation. Should not be used in childn & adolescent <18 yr. Elderly.
Adverse Reactions
Increased wt & appetite; somnolence, sedation, headache; dry mouth. Abnormal dreams, confusion, anxiety, insomnia; lethargy, dizziness, tremor; orthostatic hypotension; nausea, diarrhea, vomiting, constipation; exanthema; arthralgia, myalgia, back pain; peripheral oedema, fatigue.
Drug Interactions
Do not administer concomitantly w/ MAOIs or w/in 2 wk of cessation of MAOIs. Increased incidence of serotonin-associated effects w/ other serotonergic active substances (eg, L-tryptophan, triptans, tramadol, linezolid, methylene blue, SSRIs, venlafaxine, lithium, St. John's Wort). May increase the sedating properties of benzodiazepines & other sedatives. May increased CNS depressant effect of alcohol. Increased INR w/ warfarin. Increased risk of QT prolongation &/or ventricular arrhythmias w/ concomitant use of medicines which prolong the QTc interval. Decreased plasma conc w/ carbamazepine & phenytoin (CYP3A4 inducers). Increased Cmax & AUC w/ potent CYP3A4 inhibitors (eg, HIV PIs, azole antifungals, erythromycin, cimetidine or nefazodone).
MIMS Class
ATC Classification
N06AX11 - mirtazapine ; Belongs to the class of other antidepressants.
Presentation/Packing
Form
Remeron SolTab tab 15 mg
Packing/Price
30's
Form
Remeron SolTab tab 30 mg
Packing/Price
30's
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Sign up for free
Already a member? Sign in