Treatment of mild to moderately severe dementia of the Alzheimer type.
Dosage/Direction for Use
Adult including elderly Initially 8 mg/day in the morning. Maintenance dose: Initially 16 mg/day for at least 4 wk. Max: 24 mg/day, considered on an individual basis. Patient w/ moderately impaired hepatic function 8 mg every other day for at least 1 wk preferably in the morning. Thereafter, 8 mg/day for at least 4 wk. Max total daily dose: 16 mg.
Administration
Should be taken with food: Ensure adequate fluid intake.
Contraindications
Hypersensitivity.
Special Precautions
Monitor wt during therapy. Sick sinus syndrome, supraventricular cardiac conduction disturbances, history of ulcer disease, concurrent NSAID therapy, GI obstruction or recovering from GI surgery, seizure, severe asthma or obstructive pulmonary disease, patients w/ urinary outflow obstruction or recovering from bladder surgery. Mild cognitive impairment. May impair ability to drive or operate machinery. Severe hepatic & renal impairment. Pregnancy & lactation. Childn.
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