Saxenda

Saxenda

liraglutide

Manufacturer:

Novo Nordisk

Distributor:

Firma Chun Cheong
/
DKSH
Concise Prescribing Info
Contents
Liraglutide
Indications/Uses
Adjunct to a reduced-calorie diet & increased physical activity for wt management in adult patients w/ an initial BMI of ≥30 kg/m2 (obese), or ≥27 kg/m2 to <30 kg/m2 (overwt) in the presence of at least 1 wt-related comorbidity eg, dysglycaemia (pre-diabetes or type 2 DM), HTN, dyslipidaemia or obstructive sleep apnoea.
Dosage/Direction for Use
SC Initially 0.6 mg once daily. Should be increased to 3 mg once daily in increments of 0.6 mg w/ at least 1 wk interval.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Do not use as a substitute for insulin. Use w/ caution in patients w/ CHF NYHA class I-II; mild or moderate hepatic impairment; thyroid disease. Not recommended in patients w/ CHF NYHA class III-IV; patients ≥75 yr; treated w/ other products for wt management; w/ obesity secondary to endocrinological or eating disorders or to treatment w/ medicinal products that may cause wt gain; severe renal impairment; severe hepatic impairment; patients w/ inflammatory bowel disease & diabetic gastroparesis. Risk of developing acute pancreatitis. Higher rate of cholelithiasis & cholecystitis. Increase in heart rate. Potential risk of dehydration. Increased risk of hypoglycaemia when used in combination w/ a sulfonylurea. Pregnancy & lactation.
Adverse Reactions
Nausea, vomiting, diarrhoea, constipation. Hypoglycaemia; insomnia; dizziness, dysgeusia; dry mouth, dyspepsia, gastritis, GERD, abdominal pain upper, flatulence, eructation, abdominal distension; cholelithiasis; inj site reactions, asthenia, fatigue.
Drug Interactions
Clinically relevant interaction w/ active substances w/ poor solubility or narrow therapeutic index eg, warfarin cannot be excluded.
ATC Classification
A10BJ02 - liraglutide ; Belongs to the class of glucagon-like peptide-1 (GLP-1) analogues. Used in the treatment of diabetes.
Presentation/Packing
Form
Saxenda soln for inj (pre-filled pen) 6 mg/mL
Packing/Price
3 mL x 3 × 1's
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