In case of overdosage, hospital admission is strongly advised. Overdosage may produce respiratory depression, paranoid psychosis, delusions, hallucinations, and convulsion.
Treatment should include emptying the stomach by aspiration or gastric lavage. Nervous stimulation and convulsions should be treated with a sedative such as diazepam intamuscularly. If marked excitation is present, a sedative such as diazepam or a short-acting barbiturate may be given.
Elimination of pseudoephedrine may be assisted by acidification of the urine with ammonium chloride. Other symptomatic and supportive treatments should be given.