Selenium


Generic Medicine Info
Indications and Dosage
Intramuscular
Selenium deficiency
Adult: 100-500 mcg of selenium daily.

Intravenous
Selenium deficiency
Adult: 100-500 mcg of selenium daily.

Oral
Selenium deficiency
Adult: 100-500 mcg of selenium daily.
Overdosage
Nail or hair brittleness, hair or nail loss, diarrhoea, metallic taste, garlic-like breath odour, dermatitis, irritability, peripheral neuropathy.
Action
Description: Selenium is an essential trace element and functions as a defensive mechanism for oxidative stress, for regulation of thyroid hormone activity and redox status of vitamin C and other molecules. In food, selenium is often found as the amino acids selenomethionine and selenocysteine and derivatives. There are several forms of supplemental selenium e.g. high selenium yeast, L-selenomethionine, sodium selenate, sodium selenite and selenious acid.
Pharmacokinetics:
Absorption: Readily absorbed from GI tract
Distribution: Stored in RBC, liver, spleen, heart and nails.
Excretion: Excreted in urine as methylated metabolites and faeces (lesser extent).
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Selenium from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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