Sorafenib - oral

Patient Medicine Information
Why do I need this medicine?
Sorafenib is used to treat cancer of the liver, kidneys, and thyroid.
How do I take this medicine?
Take Sorafenib exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

This medicine should be taken on an empty stomach or at least 1 hour before or 2 hours after a meal. Swallow the tablet whole. Do not divide, chew or crush the tablet .Try to take it at the same time each day.

Sorafenib must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, inform your doctor and pharmacist.
What should I take note of while taking this medicine?
Inform your doctor if you have a liver disease.

It is important that you do not get pregnant while being treated with this medicine. You may wish to discuss birth control methods with your doctor or pharmacist.

Do not breastfeed while you are undergoing treatment with Sorafenib.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. He may also need to do routine blood tests (e.g. complete blood count, liver function tests) while you are being treated with Sorafenib. Your doctor will advise you about how often you need to have these tests.
What side effects could I experience?
Sorafenib may also cause any of the following side effects: headache, tiredness, weakness, diarrhoea, stomach pain, nausea, vomiting, constipation, loss of appetite, weakness, mouth pain, limb pain, dry skin, rash, hair loss, and hand-foot syndrome (a condition characterised by redness, swelling, and pain on the palms of the hands and/or the soles of the feet).

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

- rashes with skin peeling or blisters/rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
- squeezing sensation of the chest
- yellowing of the skin or eyes
- fever with persistent sore throat or mouth ulcers, unusual bleeding or bruising
- difficulty breathing, cough
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- other medicines to treat cancer e.g. docetaxel, doxorubicin, irinotecan
- warfarin (a blood-thinning medicine)
- dexamethasone (an anti-inflammatory medicine)
- medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenytoin, phenobarbital
- medicines to treat TB (lung infection known as tuberculosis) e.g. rifampicin
- St. John's Wort (herbal medicine)

This list does not include all medicines that may interact with Sorafenib.

Always notify your doctor or pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children. Protect from moisture.

As this is a cancer medicine, always return any unused or expired tablets to the clinic, hospital or pharmacy for disposal. Do not throw it away in the household waste.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on sorafenib - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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