Sporanox Solution

Sporanox Solution





DCH Auriga - Healthcare
Four Star
Concise Prescribing Info
Listed in Dosage.
Dosage/Direction for Use
Treatment of oral &/or oesophageal candidosis in HIV or other immunocompromised patients 200 mg daily in 2 intakes, or in 1 intake for 1 wk. Continue for another wk if there is no response after 1 wk. Fluconazole-resistant oral &/or oesophageal candidosis 100-200 mg bd for 2 wk. Continue for another 2 wk if there is no response after 2 wk. Max 400 mg daily for 14 days. Prophylaxis of deep fungal infections, in patients w/ haematological malignancy or undergoing bone marrow transplant, & are expected to become neutropenic (<500 cells/microlitre) 5 mg/kg/day in 2 intakes.
Should be taken on an empty stomach: Take at least 1 hr before meals.
Pregnancy, hypersensitivity, terfenadine, astemizole, mizolastine, cisapride, dofetilide, quinidine, pimozide, simvastatin, lovastatin, triazolam & oral midazolam.
Special Precautions
Lactation, history of hepatic or renal disease, childn, decreased gastric acidity, CHF or other cardiac disease, significant pulmonary disease, renal failure & other oedematous disorders. Monitor hepatic function.
Adverse Reactions
GI disturbances, headache, oedema, CHF & pulmonary oedema.
Drug Interactions
Rifampicin & phenytoin reduce oral bioavailability of itraconazole. Inhibits metabolism of warfarin, digoxin, terfenadine, cyclosporin A, astemizole, mizolastine, cisapride, dofetilide, quinidine, pimozide, oral midazolam & triazolam, simvastatin, lovastatin, Ca-channel blockers. Oral anticoagulants, HIV-protease inhibitors, vinca alkaloids, busulphan, docetaxel, trimetrexate, cyclosporin, tacrolimus, rapamycin.
MIMS Class
ATC Classification
J02AC02 - itraconazole ; Belongs to the class of triazole derivatives. Used in the systemic treatment of mycotic infections.
Sporanox Solution oral soln 10 mg/mL
150 mL x 1's
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Sign up for free
Already a member? Sign in