Stadloric 200

Stadloric 200





HK Medical Supplies
Health Express
Concise Prescribing Info
Symptomatic relief of OA, RA & ankylosing spondylitis.
Dosage/Direction for Use
OA 200 mg once daily or in 2 divided doses, may be increased to 200 mg bd. RA 200 mg in 2 divided doses, may be increased to 200 mg bd. Ankylosing spondylitis 200 mg once daily or in 2 divided doses, may be increased to 400 mg once daily or in 2 divided doses. Max recommended daily dose for all indications: 400 mg. Elderly >65 yr 200 mg once daily, may be increased to 200 mg bd if needed.
May be taken with or without food: For patients w/ swallowing difficulties, contents may be added to applesauce/rice gruel/yogurt/mashed banana.
Hypersensitivity to celecoxib & sulphonamides. Active peptic ulceration or GI bleeding. Inflammatory bowel disease; CHF (NYHA II-IV); established ischaemic heart disease, peripheral arterial disease &/or cerebrovascular disease. Patients w/ severe heart failure. Patients w/ estimated CrCl <30 mL/min. Patients who have allergic type reactions after taking aspirin or other NSAIDs (including COX-2 inhibitors). For the treatment of peri-op pain in the setting of CABG surgery. Women of childbearing potential. Pregnancy & lactation.
Special Precautions
Skin & systemic hypersensitivity reactions. GI risks (eg, bleeding, ulceration, perforation of stomach or intestines). Avoid concomitant use w/ a non-aspirin NSAID. CV, hepatic & renal effects. Closely monitor BP. Use w/ caution in patients at risk for fluid retention & oedema. Known poor CYP2C9 metabolisers. May mask fever & other signs of inflammation. Patients on concurrent therapy w/ warfarin. Rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption. May impair ability to drive & use machines.
Adverse Reactions
HTN. Sinusitis, upper resp tract infection, pharyngitis, UTI; hypersensitivity; insomnia; dizziness, hypertonia, headache; MI; rhinitis, cough, dyspepsia, flatulence, vomiting, dysphagia; rash, pruritus; arthralgia; flu-like illness, peripheral oedema, fluid retention; injury.
Drug Interactions
Increased risk of bleeding w/ warfarin. Reduced effect of anti-hypertensives (eg, ACE-inhibitors, angiotensin II receptor antagonists, diuretics & β-blockers). Increased nephrotoxic effect of ciclosporin & tacrolimus. Increased plasma conc of CYP2D6 & CYP2C19 substrates. Further increased celecoxib exposure in poor CYP2C9 metabolisers. Increased in Cmax of lithium. Reduced plasma conc w/ CYP2C9 inducers eg, rifampicin, carbamazepine & barbiturates.
ATC Classification
M01AH01 - celecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.
Stadloric 200 cap 200 mg
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