Infection; thrombocytopenia, anaemia; decreased appetite & food intake; haemorrhage, HTN; dysphonia; diarrhoea, stomatitis, vomiting, nausea; hyperbilirubinaemia, increase in transaminases; hand-foot skin reaction, rash; asthenia/fatigue, pain, fever, mucosal inflammation; wt loss. Leucopenia; hypothyroidism; hypokalaemia, hypophosphatemia, hypocalcaemia, hyponatraemia, hypomagnesaemia, hyperuricaemia, dehydration; headache, tremor, peripheral neuropathy; taste disorders, dry mouth, gastro-oesophageal reflux, gastroenteritis; alopecia, dry skin, exfoliative rash; muscle spasms; proteinuria; increase in amylase, increase in lipase, abnormal INR.