Sulfabenzamide


Generic Medicine Info
Indications and Dosage
Vaginal
Bacterial vaginosis
Adult: As vaginal cream containing sulfathiazole 34.2 mg/g, sulfacetamide 28.6 mg/g and sulfabenzamide 37 mg/g: Apply 1 applicatorful of cream intravaginally bid for 4-6 days, after which, reduce the dosage to ½ or ¼ of an applicatorful bid.
Contraindications
Hypersensitivity to sulphonamide and kidney disease.
Special Precautions
Pregnancy (avoid if near term).
Adverse Reactions
Pruritus, local irritation.
Potentially Fatal: Stevens-Johnson syndrome, blood dyscrasia.
Action
Description: Sulfabenzamide, a sulfonamide, has properties similar to sulfamethoxazole. At pH 4.6, it exerts optimal bacteriostatic actions. By having a structure similar to p-aminobenzoic acid, sulfabenzamide interferes with nuclei acid synthesis in sensitive micro-organisms by preventing the conversion of p-aminobenzoic acid to coenzyme dihydrofolic acid.
Storage
Store below 25°C.
Disclaimer: This information is independently developed by MIMS based on Sulfabenzamide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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