Sultopride


Concise Prescribing Info
Indications/Uses
Psychoses.
Dosage/Direction for Use
Adult : PO 400-800 mg/day.
Dosage Details
Oral
Psychoses
Adult: Acute and chronic psychoses: 400-800 mg daily. May also be given via IM inj.
Renal Impairment
Dose reduction may be needed.
Contraindications
Comatose states, CNS depression, phaeochromocytoma, porphyria, bradycardia. Lactation.
Special Precautions
Renal impairment, CV disease, Parkinson's disease, depression. Elderly. May impair ability to drive or operate machinery.
Adverse Reactions
Extrapyramidal effects, parkinsonian symptoms, dystonia, akathesia, tardive dyskinesia, sleep disturbances, overstimulation, agitation, wt gain, sedation, hyperprolactinaemia.
Potentially Fatal: Ventricular arrhythmia e.g. torsade de pointes, neuroleptic malignant syndrome.
Drug Interactions
Increased risk of ventricular arrhythmia with drugs that prolong QT interval. Increased CNS depression with other CNS depressants e.g. alcohol, general anaesthetics, hypnotics, opioids.
Action
Description: Sultopride has general properties similar to those of sulpiride. It is a dopamine antagonist and is used in the emergency management of agitation in patients who are psychotic or aggressive and in psychoses e.g. schizophrenia. Given as the hydrochloride but doses are expressed in terms of base. Sultopride hydrochloride 441 mg is equivalent to 400 mg sultopride.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Sultopride from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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