Tamoxifen Ebewe

Tamoxifen Ebewe

tamoxifen

Manufacturer:

Sandoz

Distributor:

Zuellig
/
Firma Vai Hong
Concise Prescribing Info
Contents
Tamoxifen
Indications/Uses
Adjuvant therapy for treatment of early breast cancer & endometrium carcinoma in women. Adjuvant therapy in women w/ positive axillary node breast cancer; metastatic breast cancer in men & women.
Dosage/Direction for Use
20 mg daily. Max dose: 40 mg daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Severe thrombocytopenia, leukopenia or hypercalcaemia. Pregnancy.
Special Precautions
Liver & kidney disease, DM, history of thromboembolic disease, visual disturbances. Increased incidence of endometrial changes. Perform period ophth exam. Perform a gynaecological exam before & during (at 6-mthly intervals) treatment. Lactation.
Adverse Reactions
Hot flushes, vag bleeding, vag discharge, pruritus vulvae. Fluid retention, nausea, vomiting, tumour flare, lightheadedness, rash & alopecia, tiredness & headache, impotence or loss of libido (in males). Leucopenia &/or thrombocytopenia, endometrial changes, ophth disturbances, thromboembolic events.
Drug Interactions
Oestrogen-containing medications, coumarin anticoagulants, cytotoxic agents, bromocriptine, some SSRIs.
ATC Classification
L02BA01 - tamoxifen ; Belongs to the class of anti-estrogens. Used in treatment of neoplastic diseases.
Presentation/Packing
Form
Tamoxifen Ebewe tab 10 mg
Packing/Price
30's
Form
Tamoxifen Ebewe tab 20 mg
Packing/Price
30's
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