Tobrex

Tobrex

tobramycin

Manufacturer:

Novartis

Distributor:

Zuellig
/
Firma Chun Cheong
Concise Prescribing Info
Contents
Tobramycin
Indications/Uses
External infections of the eye & its adnexa caused by susceptible bacteria.
Dosage/Direction for Use
Ophth soln Mild disease 1 or 2 drops every 4 hr. Severe infection 2 drops hrly until improvement. Treatment should be reduced prior to discontinuation. Ophth oint Mild disease Small amount of oint bd or tds. Severe infection Small amount of oint every 3-4 hr until improvement. Treatment should be reduced prior to discontinuation.
Contraindications
Hypersensitivity to tobramycin or to aminoglycosides.
Special Precautions
Not for inj or ingestion. Cross-hypersensitivity w/ other aminoglycosides. Discontinue treatment if hypersensitivity develops. Risk of neurotoxicity, ototoxicity & nephrotoxicity w/ systemic aminoglycoside therapy. Caution in patients w/ known or suspected neuromuscular disorders eg, myasthenia gravis or Parkinson's disease. Prolonged use may result in overgrowth of non-susceptible organisms, including fungi. Contact lens wear is not recommended during treatment. May affect ability to drive & use machines due to temporary blurring of vision & other visual disturbances. Avoid use during pregnancy. Lactation. Ophth soln: Contains benzalkonium Cl.
Adverse Reactions
Drug Interactions
Additive toxicity w/ other neurotoxic, ototoxic, or nephrotoxic systemic, oral or topical drugs. Topical corticosteroids w/ tobramycin may mask clinical signs of bacterial, fungal, or viral infections & may suppress hypersensitivity reactions. If >1 topical ophth prep is being used, products must be administered at least 5 min apart; eye oint should be administered last.
MIMS Class
Eye Anti-Infectives & Antiseptics
ATC Classification
S01AA12 - tobramycin ; Belongs to the class of antibiotics. Used in the treatment of eye infections.
Presentation/Packing
Form
Tobrex ophthalmic oint 0.3 %
Packing/Price
3.5 g x 1's
Form
Tobrex sterile ophth soln 0.3 %
Packing/Price
5 mL x 1's
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