Posology: In mild disease: 1 or 2 drops in the eye(s) every 4 hours, or a small amount of ointment 2 to 3 times per day.
In more severe infections: 2 drops in the eye(s) hourly or a small amount of ointment every 3 to 4 hours until improvement, following which treatment should be reduced prior to discontinuation.
The length of the treatment is dependent on the origin of the infection and may vary from a couple of days up to some weeks.
Paediatric population: TOBREX eye drops and eye ointment may be used in children 1 year of age and older at the same dose as in adults. Currently available data is described in Pharmacology: Pharmacodynamics under Actions. The safety and efficacy in children younger than 1 year of age have not been established. No data are available.
Older people: No overall clinical differences in safety or efficacy have been observed between the elderly and other adult populations.
Use in hepatic and renal impairment: TOBREX eye drops and eye ointment have not been studied in these patient populations. However, due to low systemic absorption of tobramycin after topical administration of this product, dose adjustment is not necessary.
Method of administration: For ocular use.
TOBREX eye drops: after cap is removed from eye drops bottle, if tamper evident snap collar is loose, remove before using product.
To prevent contamination of the dropper tip/tube tip and solution/ointment, care must be taken not to touch the eyelids, surrounding areas, or other surfaces with the dropper tip/tube tip. Keep the bottle/tube tightly closed when not in use.
In case of concomitant therapy with other topical ocular medicines, an interval of a least 5 minutes should be allowed between successive applications. Eye ointments should be administered last.