Isolated cases of overdose have been reported. The maximum dose taken was 24 g. Symptomatic treatment was given and all patients recovered.
Signs and Symptoms: Overdosage leads to symptoms eg, drowsiness, lightheadedness, nausea, vomiting, hyperkinesia, hyponatraemia, ataxia and nystagmus.
Management: There is no specific antidote. Appropriate symptomatic and supportive treatment should be given. Removal of the drug by gastric lavage and/or inactivation of the drug through administration of activated charcoal should be considered. Monitoring of vital functions is recommended with particular attention being paid to cardiac conduction disturbances, electrolyte disturbances and respiratory problems.