Trimetazidine - oral

Patient Medicine Information
Why do I need this medicine?
Trimetazidine is used together with other medicines to help relieve symptoms of angina pectoris (chest pain which occurs when the heart does not receive enough oxygen and blood supply).

This medicine is used to those who are inadequately controlled by or intolerant to first-line antianginal therapies.
How do I take this medicine?
Take Trimetazidine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it together with food or immediately after a meal. Try to take it at the same time each day.

Trimetazidine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • Parkinson's disease (a disorder that affects movement of a person, causing symptoms such as tremors, muscle stiffness, slowed movement and impaired balance or walking)
  • restless legs syndrome (a nerve disorder that causes uncontrollable urge to move your legs due to an uncomfortable sensation)
  • tremors (involuntary shaking of the hands or legs)
  • severe kidney disease
as Trimetazidine may not be suitable for you.

Do not breastfeed while you are being treated with this medicine.
What should I take note of while taking this medicine?
Inform your doctor if you have moderate kidney disease.

Let your doctor know if you are pregnant.

Be sure to check with your doctor or pharmacist before giving this medicine to an elderly. Elderly may be more sensitive to the side effects.

Trimetazidine is not intended to be used as an initial treatment of sudden angina (chest pain), heart attack, or during the first days of hospitalisation.
What side effects could I experience?
Trimetazidine may cause drowsiness and dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: stomach pain, diarrhoea, indigestion, nausea, vomiting, weakness or lack of energy, skin rash and itching.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • muscle stiffness
  • involuntary shaking of the hands or legs
  • slowed movement
  • imbalance while walking
  • strong, irresistible urge to move your legs accompanied by uncomfortable sensations
Rarely, this medicine may cause your blood pressure to fall suddenly when you get up from a sitting or lying down position and you may feel giddy. To minimise this problem, stand up slowly.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on trimetazidine - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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