Urief

Urief Drug Interactions

silodosin

Manufacturer:

Synmosa

Distributor:

Synmosa
Full Prescribing Info
Drug Interactions
Silodosin is metabolized mainly by cytochrome P450 3A4 (CYP3A4), UDP-glucuronosyltransferases (UGTs), alcohol dehydrogenase (ADH), and aldehyde dehydrogenase (ALDH). (See Pharmacology: Pharmacokinetics under Actions.) Coadministration with potent inhibitors of CYP3A4 activity blocks the metabolism of silodosin. This may result in elevated plasma drug concentrations. (See Table 9.)

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