Bacillus calmette-guérin vaccine - parenteral

Patient Medicine Information
Why do I need this medicine?
Bacillus Calmette-Guérin (BCG) vaccine is used to protect you against TB (lung infection known as tuberculosis).
How do I use this medicine?
BCG vaccine is to be given either intradermally (into the layer of the skin called dermis) or percutaneously (injection through the skin using a puncture device), depending on the product being used.

Your doctor or nurse will administer the injection for you or for your child.
When should I not use this medicine?
Do not use this medicine if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to BCG vaccine or any of its ingredients.

Alert your doctor if you have the following conditions:
  • HIV infection, including infants born to HIV-positive mothers
  • cancer e.g. leukaemia (cancer of the blood-forming tissues, including the bone marrow)
  • weakened immune system
  • active TB (tuberculosis)
  • sudden severe illness with fever or skin infection
as BCG vaccine may not be suitable for you.

Do not give BCG vaccine to infants whose mothers have been receiving treatments for immune disorders either during pregnancy or via breastfeeding.

Do not use BCG vaccine with medicines used to treat TB or medicines which may affect your immune system. Please see the section “Can I use this with other medicines?” below for more information.
What should I take note of while using this medicine?
Inform your doctor if you have been recently vaccinated. Do not receive any vaccinations without first asking your doctor.

Let your doctor know if you are pregnant or breastfeeding.
What side effects could I experience?
BCG vaccine may cause any of the following side effects: fever, muscle pain, flu-like symptoms, swelling in the lymph nodes of the neck or armpit and swelling, ulcer or abscess at the injection site.

If you or your child develop rashes, breathlessness, swollen mouth or eyes, inform your doctor immediately. These could be signs of an allergic reaction.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Do not use BCG vaccine if you are taking any of these medicines:
  • anti-inflammatory medicines e.g. prednisone 
  • medicines for cancer e.g. cisplatin, mercaptopurine
  • medicines used in organ transplant or certain immune disorders e.g. tacrolimus, ciclosporin
  • medicines used to treat rheumatoid arthritis e.g. adalimumab, infliximab
  • medicines used to treat TB e.g. isoniazid, streptomycin, rifampicin, ethambutol
This list does not include all medicines that may interact with BCG vaccine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in the refrigerator, between 2-8 °C. Do not freeze.

Protect from light.
This information is independently developed by MIMS based on bacillus calmette-guérin vaccine - parenteral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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