Ventra

Ventra

esomeprazole

Manufacturer:

Ethypharm

Distributor:

International Med
Concise Prescribing Info
Contents
Esomeprazole
Indications/Uses
Adults & adolescents ≥12 yr: GERD; H. pylori-induced stomach or intestinal ulcer. Adults: Treatment & prevention of NSAID-induced stomach ulcers; treatment of Zollinger-Ellison syndrome; prolonged treatment after prevention of rebleeding ulcers w/ IV esomeprazole.
Dosage/Direction for Use
Adult & childn ≥12 yr Heartburn caused by GERD (Slightly damaged gullet) 40 mg once daily for 4 wk, may be reduced to 20 mg once daily when gullet has healed, (Undamaged gullet) 20 mg once daily. Treatment & prevention of H. pylori-induced ulcer 20 mg bd for 1 wk. Adult ≥18 yr Treatment of NSAID-induced stomach ulcers 20 mg once daily for 4-8 wk. Prevention of NSAID-induced stomach ulcers 20 mg once daily. Zollinger-Ellison syndrome 40 mg bd. Max: 80 mg bd. Prolonged treatment after prevention of rebleeding of ulcers w/ IV esomeprazole 40 mg once daily for 4 wk.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to esomeprazole, proton pump inhibitors (eg, pantoprazole, lansoprazole, rabeprazole, omeprazole). Concomitant use w/ nelfinavir.
Special Precautions
Patients w/ history of skin reaction after treatment w/ medicines similar to Ventra; rash especially in areas exposed to the sun. May hide symptoms of other diseases. Wt loss & problem swallowing; stomach pain or indigestion; vomiting food or blood; passing black stools. Risk of symptomatic & asymptomatic hypomagnesemia. Monitor Mg levels prior to initiation of proton pump inhibitors & periodically thereafter. Increased risk of GI infections eg, Salmonella, Campylobacter & possibly Clostridium difficile; osteoporosis-related fractures of the hip, wrist or spine. Subacute cutaneous lupus erythematosus (SCLE). Concomitant use w/ clopidogrel; methotrexate; corticosteroids. May interfere w/ Chromogranin A test. Contains sucrose, propyl-p-hydroxybenzoate (E126) & methyl-p-hydroxybenzoate (E218). Severe liver or kidney problems. Pregnancy & lactation. Childn <12 yr.
Adverse Reactions
Headache; diarrhoea, stomach pain, constipation, flatulence; nausea or vomiting; benign polyps in the stomach.
Drug Interactions
Concomitant use w/ nelfinavir, atazanavir or saquinavir; ketoconazole, itraconazole or voriconazole; erlotinib; citalopram, imipramine or clomipramine; diazepam; phenytoin; warfarin; cilostazol; cisapride; digoxin; clopidogrel; tacrolimus; methotrexate; rifampicin; St. John's wort.
ATC Classification
A02BC05 - esomeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
Presentation/Packing
Form
Ventra gastro-resistant cap 20 mg
Packing/Price
28's
Form
Ventra gastro-resistant cap 40 mg
Packing/Price
28's
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