Vorifend

Vorifend

glucosamine

Manufacturer:

Stellapharm

Distributor:

HK Medical Supplies
/
Health Express
Full Prescribing Info
Contents
Glucosamine sulfate.
Description
Each Vorifend 500 mg film-coated tablet contains 500 mg of glucosamine sulfate (as glucosamine sulfate potassium chloride equivalent to 392.6 mg of glucosamine base).
Action
Pharmacology: Pharmacodynamics: Glucosamine is a natural substance found in chitin, mucoproteins, and mucopolysaccharides. It is involved in the manufacture of glycosaminoglycan, which forms cartilage tissue in the body; glucosamine is also present in tendons and ligaments. Glucosamine must be synthesised by the body but the ability to do this declines with age. Glucosamine and its salts have therefore been given for their supposed chondroprotective action in musculoskeletal and joint disorders including osteoarthritis. Glucosamine may be isolated from chitin or prepared synthetically; glucosamine sulfate and hydriodide, have also been used.
Indications/Uses
Symptomatic relief of mild to moderate osteoarthritis of the knee.
Dosage/Direction for Use
Dosage: Adults over 18 years: Take 3 tablets once daily. Review treatment if no benefit after 2-3 months.
Administration: Vorifend 500 mg is administered orally.
Overdosage
No information available.
Contraindications
Shellfish allergy.
Special Precautions
Impaired glucose tolerance (monitor blood-glucose concentration before treatment and periodically thereafter).
Predisposition to cardiovascular disease (monitor cholesterol).
Asthma.
Use In Pregnancy & Lactation
Manufacturer advises avoid - no information available.
Adverse Reactions
Nausea, abdominal pain, dyspepsia, flatulence, diarrhoea, constipation, drowsiness, headache, fatigue.
Less common: flushing, rash, pruritus.
Also reported: hypercholesterolaemia, visual disturbances, hair loss.
Drug Interactions
There have been reports of an increased international normalised ratio (INR) values in patients taking warfarin and dietary supplements containing glucosamine with or without chondroitin.
Patients on warfarin should not take glucosamine.
Storage
Store in a well-closed container, in a dry place. Do not store above 30°C.
ATC Classification
M01AX05 - glucosamine ; Belongs to the class of other non-steroidal antiinflammatory and antirheumatic products.
Presentation/Packing
FC tab 500 mg (pink, oval-shaped, biconvex, plain on both sides) x 6 x 10's.
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