Generic Medicine Info
Use of oral powder for solution and effervescent tab in children below 2 years of age.
Special Precautions
Patient with known or history of atopy and asthma, history of bronchospasm, history of. peptic ulcer disease, esophageal varices. Children. Pregnancy and lactation. Patient Counselling Ophthalmic: This drug may cause blurred vision, if affected, do not drive or operate machinery. Should not be used in patients who wear soft contact lenses. Monitoring Parameters Paracetamol poisoning: Monitor serum paracetamol levels, AST, ALT, bilirubin, prothrombin time, INR, serum creatinine, BUN, serum glucose, Hb, haematocrit and electrolytes.
Adverse Reactions
Significant: Hypersensitivity reactions (e.g. urticaria, rash, hypotension, wheezing, dyspnoea); fluid overload resulting in hyponatraemia and seizures, decreased prothrombin time, acute flushing, skin erythema (IV); risk of upper gastrointestinal haemorrhage (oral); haemoptysis, rhinorrhoea, stomatitis (inhalation). Cardiac disorders: Cardiac arrest. Eye disorders: Ophthalmic: Itching, redness, eye irritation, blurred vision. Gastrointestinal disorders: Nausea, vomiting. General disorders and administration site conditions: Fever, sweating. Investigations: Liver function disturbances. Metabolism and nutrition disorders: Acidosis. Musculoskeletal and connective tissue disorders: Arthralgia. Nervous system disorders: Convulsion. Respiratory, thoracic and mediastinal disorders: Respiratory arrest. Vascular disorders: Hypo/hypertension, syncope.
Potentially Fatal: Serious hypersensitivity reactions (e.g. bronchospasm, angioedema), fluid overload resulting in hyponatraemia and seizures (IV).
Drug Interactions
Build-up of bronchial secretions due to reduced cough reflex with antitussive drugs. Reduced effect with activated charcoal. May enhance the vasodilatory effects of nitroglycerin. May reduce the pharmacological effects of antibiotics.
ATC Classification
V03AB23 - acetylcysteine ; Belongs to the class of antidotes. Used to neutralize paracetamol overdose.
S01XA08 - acetylcysteine ; Belongs to the class of other ophthalmologicals.
R05CB01 - acetylcysteine ; Belongs to the class of mucolytics. Used in the treatment of wet cough.
Disclaimer: This information is independently developed by CIMS based on acetylcysteine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by
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