|
Contraindications
Penicillin allergy, lactation.
|
|
Special Precautions
Pregnancy, renal and hepatic disease and history of peptic ulcer . Infectious mononucleosis.
|
|
Adverse Reactions
Headache, nausea, dizziness, vomiting, diarrhoea, black hairy tongue, maculopapular rash, urticaria, eosinophilia, hemolytic anemia, thrombocytopenia.
Potentially Fatal: Anaphylaxis, pseudomembranous colitis, acute cytoloytic hepatitis and Stevens-Johnson syndrome. |
|
Drug Interactions
Live oral typhoid vaccine should not be given 3 days before or 3 days after amoxicillin admin as immune response may be attenuated. Amoxicillin increases the anticoagulant response of coumarins. Amoxicillin may reduce OC pill absorption leading to breakthrough bleeding or pregnancy. Amoxicillin reduces the renal clearance of methotrexate and pemetrexate. Amoxicillin level significantly reduced when given with or 2 hr after acacia admin. Bromhexine enhances the penetration of amoxicillin into bronchial secretions.
|
|
CIMS Class
|
|
ATC Classification
R05CB02 - bromhexine ; Belongs to the class of mucolytics. Used in the treatment of wet cough.
J01CA04 - amoxicillin ; Belongs to the class of penicillins with extended spectrum. Used in the systemic treatment of infections. |
Sign Out
