Amoxicillin + carbocisteine


Concise Prescribing Info
Indications/Uses
Resp tract infections associated w/ excessive and/or viscous mucus.
Dosage/Direction for Use
Adult: PO Per cap contains amoxicillin 250/500 mg and carbocisteine 150 mg: 1-2 cap 3 times/day.
Contraindications
Allergy to penicillins, pregnancy.
Special Precautions
History of peptic ulcer, severe renal impairment. Infectious mononucleosis and lactation.
Adverse Reactions
Headache, nausea, dizziness, vomiting, diarrhoea, GI discomfort/ bleeding, black hairy tongue, maculopapular rash, urticaria, eosinophilia, hemolytic anemia, thrombocytopenia.
Potentially Fatal: Anaphylaxis, pseudomembranous colitis, acute cytoloytic hepatitis and Stevens-Johnson syndrome.
Drug Interactions
Live oral typhoid vaccine should not be given 3 days before or 3 days after amoxicillin admin as immune response may be attenuated. Amoxicillin increases the anticoagulant response of coumarins. Amoxicillin may reduce OC pill absorption leading to breakthrough bleeding or pregnancy. Amoxicillin reduces the renal clearance of methotrexate and pemetrexate. Amoxicillin level significantly reduced when given with or 2 hr after acacia admin.
CIMS Class
ATC Classification
R05CB03 - carbocisteine ; Belongs to the class of mucolytics. Used in the treatment of wet cough.
J01CA04 - amoxicillin ; Belongs to the class of penicillins with extended spectrum. Used in the systemic treatment of infections.
Disclaimer: This information is independently developed by CIMS based on amoxicillin + carbocisteine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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