Ascorbic acid


Generic Medicine Info
Administration
May be taken with or without food.
Special Precautions
Patient with diabetes mellitus, G6PD deficiency, haemochromatosis, history of renal stones (e.g. oxalate kidney stones), predisposition to recurrent renal calculi. Renal impairment. Children (<2 years of age) and elderly. Pregnancy and lactation. Monitoring Parameters Monitor renal function (patient with a predisposition to oxalate nephropathy), haemoglobin, and blood counts (G6PD deficient patient).
Adverse Reactions
Significant: Acute or chronic oxalate nephropathy (prolonged use; large doses). Gastrointestinal disorders: Diarrhoea, nausea, vomiting, heartburn. General disorders and administration site conditions: Fatigue, pain at the inj site. Nervous system disorders: Dizziness, headache. Vascular disorders: Flushing.
Drug Interactions
Increased absorption of Fe. Increased excretion of Fe with desferrioxamine. Induced tissue desaturation with aspirin, nicotine, Fe, phenytoin, tetracycline, estrogen in oral contraceptives, some appetite suppressants and anticonvulsants. May increase the absorption of Al-containing antacids. May diminish the activity of anticoagulants (e.g. warfarin). May increase the serum concentration of estrogen derivatives. May decrease the serum concentration of amphetamines.
CIMS Class
ATC Classification
S01XA15 - ascorbic acid ; Belongs to the class of other ophthalmologicals.
G01AD03 - ascorbic acid ; Belongs to the class of organic acid antiinfectives. Used in the treatment of gynecological infections.
Disclaimer: This information is independently developed by CIMS based on ascorbic acid from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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