Benzatropine


Generic Medicine Info
Contraindications
Childn <3 yr.
Special Precautions
Patient w/ tachycardia, obstructive disease of the GI tract (e.g. pyloric or duodenal obstruction), glaucoma, prostatic hyperplasia and/or urinary stricture or retention. Use w/ caution during hot weather (esp in patients concurrently taking atropine-like drugs to chronically ill, alcoholics, w/ CNS disease, those w/ prolonged outdoor exposure). Not intended for treatment of tardive dyskinesia. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate machinery. Monitoring Parameters Monitor pulse and anticholinergic effects.
Adverse Reactions
Tachycardia, dry mouth, constipation, nausea, vomiting, paralytic ileus, toxic psychosis (including exacerbation of pre-existing psychotic symptoms, disorientation, confusion, memory impairment, visual hallucinations, nervousness, depression, listlessness, finger numbness), blurred vision, dilated pupils, dysuria, urinary retention, allergic reactions (e.g. skin rash), fever.
Potentially Fatal: Severe anhidrosis which may lead to hyperthermia.
Drug Interactions
May cause heat intolerance, fever and GI complaints when concomitantly used w/ phenothiazines, haloperidol or other drugs w/ anticholinergic or antidopaminergic activity. May cause paralytic ileus, hyperthermia or heat intolerance (sometimes fatal) when concomitantly used w/ phenothiazines and/or TCAs. Increased sedative effect w/ other CNS depressants (e.g. sedatives and hypnotics, anxiolytics). May interfere w/ oral bioavailability of ketoconazole. Additive depressive effect on GI motility or bladder w/ opiate agonists. Antagonistic effect w/ parasympathomimetics (including both direct cholinergic receptor agonists and cholinesterase inhibitors). Reduced excretion and increased effects w/ carbonic anhydrase inhibitors.
ATC Classification
N04AC01 - benzatropine ; Belongs to the class of anticholinergic agents, ethers of tropine or tropine derivatives. Used in the management of Parkinson's disease.
Disclaimer: This information is independently developed by CIMS based on benzatropine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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