Generic Medicine Info
Should be taken on an empty stomach. Take w/ a full glass of water on an empty stomach 1 hr before or 2 hr after meals. Do not take acidic beverages w/in 1 hr of a dose.
Hypersensitivity to benzylpenicillin and other penicillins.
Special Precautions
Patients w/ history of allergy esp β-lactam allergy and/or asthma, seizure disorder. Diabetic patients. Renal impairment. Pregnancy and lactation. Monitoring Parameters Monitor electrolyte, hepatic, renal, cardiac and haematologic function; signs and symptoms of anaphylaxis during 1st dose.
Adverse Reactions
Nausea, vomiting, stomatitis, black or hairy tongue, rash, fever, serum-like sickness, convulsions, interstitial nephritis, haemolytic anaemia, granulocytopenia, agranulocytosis, leucopenia, thrombocytopenia.
Potentially Fatal: Anaphylaxis, pseudomembranous colitis.
Drug Interactions
May reduce the efficacy of OC. May increase the risk of methotrexate toxicity. Increased plasma concentration w/ probenecid. Antagonism of bactericidal effect w/ bacteriostatic antibacterials (e.g. erythromycin, tetracyclines).
CIMS Class
ATC Classification
S01AA14 - benzylpenicillin ; Belongs to the class of antibiotics. Used in the treatment of eye infections.
J01CE01 - benzylpenicillin ; Belongs to the class of beta-lactamase sensitive penicillins. Used in the systemic treatment of infections.
Disclaimer: This information is independently developed by CIMS based on benzylpenicillin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by
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